One-Stage Full Mouth Instrumentation (OSFMI): Clinical Outcomes of an Innovative Protocol for the Treatment of Severe Periodontitis.

Magda Mensi, Magda Feres, Stefano Calza, Annamaria Sordillo, Eleonora Scotti, Gianluca Garzetti
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Abstract

Aims: This case series study aimed to assess the clinical outcomes of a novel protocol for the treatment of patients with severe periodontitis.

Materials and methods: Twenty (20) patients with severe periodontitis underwent a single session of One-Stage Full-Mouth Instrumentation (OSFMI) involving supra- and sub-gingival air-polishing with erythritol and chlorhexidine powder and ultrasonic root surface debridement and calculus removal, in association with systemic amoxicillin and metronidazole. Pocket Probing Depth (PPD), Clinical Attachment Level (CAL), Recession (REC), Bleeding on Probing (BOP) and Plaque Index (PI) were collected at baseline (T0), 6 weeks (T1), 3 months (T2) and 6 months (T3).

Results: At 6 months, 30% of subjects reached the primary clinical endpoint (less than or equal to4 sites with PD greater than or equal to 5 mm). The percentage of BOP decreased from 49.08 (CI95% 36.06; 62.1) at T0 to 12.97 (CI95% 7.57; 18.37) at T3. The mean number pockets with PPD≥ 5 mm and PPD greater than or equal to 7 mm decreased significantly, from 46.0 and 20.6 at T0 to 11.5 and 2.8 at T3 respectively (p less than 0.001).

Conclusion: The OSFMI protocol led to clinical results comparable to those obtained with traditional SRP. Researchers are encouraged to test this protocol in randomized clinical trials with longer periods of observation.

一期全口器械(OSFMI):一种治疗严重牙周炎的创新方案的临床结果
目的:本病例系列研究旨在评估一种治疗严重牙周炎患者的新方案的临床结果。材料和方法:20例重度牙周炎患者接受一期全口器械治疗(OSFMI),包括用赤四糖醇和氯己定粉末进行龈上和龈下空气抛光,超声根面清肿和牙石清除,并辅以全身阿莫西林和甲硝唑。在基线(T0)、6周(T1)、3个月(T2)和6个月(T3)收集探查袋深度(PPD)、临床附着水平(CAL)、衰退(REC)、探查出血(BOP)和斑块指数(PI)。结果:在6个月时,30%的受试者达到了主要临床终点(小于或等于4个PD大于或等于5 mm的部位)。防喷器比例从49.08 (CI95% 36.06;62.1), T0 ~ 12.97 (CI95% 7.57;18.37)在T3。PPD≥5 mm和PPD大于或等于7 mm的平均袋数显著减少,分别从T0时的46.0和20.6个减少到T3时的11.5和2.8个(p < 0.001)。结论:OSFMI方案的临床效果与传统SRP相当。鼓励研究人员在随机临床试验中对该方案进行长期观察。
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