Idiopathic CD4 Lymphocytopenia: Current Insights.

IF 6.2 Q1 IMMUNOLOGY

ImmunoTargets and Therapy Pub Date : 2020-05-14 eCollection Date: 2020-01-01 DOI:10.2147/ITT.S214139

Saravanakumari Vijayakumar, Stalin Viswanathan, Rajeswari Aghoram

引用次数: 13

Abstract

Idiopathic CD4 lymphocytopenia is a condition characterized by low CD4 counts. It is rare and most of the information about this illness comes from case reports. Presentation is usually in the 4th decade of life with opportunistic infections, autoimmune disease or neoplasia. The pathophysiology of this condition is not well understood. Management revolves around treatment of the presenting condition and close follow-up of these patients. This review presents a narrative summary of the current literature on idiopathic CD4 lymphocytopenia.

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特发性CD4淋巴细胞减少症:当前的见解。

特发性CD4淋巴细胞减少症是一种以CD4计数低为特征的疾病。这是罕见的，大多数关于这种疾病的信息来自病例报告。表现通常在40岁左右，伴有机会性感染、自身免疫性疾病或肿瘤。这种情况的病理生理学尚不清楚。管理围绕着治疗这些患者的症状和密切关系follow-up。本文综述了目前关于特发性CD4淋巴细胞减少症的文献。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ImmunoTargets and Therapy IMMUNOLOGY-

CiteScore

16.50

自引率

0.00%

发文量

审稿时长

16 weeks

期刊介绍： Immuno Targets and Therapy is an international, peer-reviewed open access journal focusing on the immunological basis of diseases, potential targets for immune based therapy and treatment protocols employed to improve patient management. Basic immunology and physiology of the immune system in health, and disease will be also covered.In addition, the journal will focus on the impact of management programs and new therapeutic agents and protocols on patient perspectives such as quality of life, adherence and satisfaction.