Epsilon-Aminocaproic Acid in Liver Transplantation: A Three-Year, Retrospective Review.

Abstract

The primary aim was to determine whether EACA affected transfusion requirements. Secondary outcomes were effect of EACA use on fibrinogen level, operative time, and hepatic artery or portal vein thrombus formation. We examined the association between EACA and RBC and FFP transfusion volume; factor 7 administrations, presence of thrombosis, mortality, change in fibrinogen levels, and MELD score. Chi-square tests and Fisher’s exact test were used for comparing categorical variables. Student’s t-test or Mann-Whitney U test was used to examine associations between EACA usage and all continuous outcomes. All analyses were conducted in SAS v. 9.3 (SAS Institute, Cary, NC).