Michele Marchioni, Giulia Primiceri, Pietro Castellan, Luigi Schips, Guglielmo Mantica, Christopher Chapple, Rocco Papalia, Francesco Porpiglia, Roberto M Scarpa, Francesco Esperto
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引用次数: 10
Abstract
Introduction: Robotic assisted radical prostatectomy (RARP) is getting more and more popular becoming the most common radical prostatectomy technique. Unfortunately, a not negligible proportion of patients in whom RARP is performed experience urinary incontinence. We aimed to systematically review the current literature evidence on urinary incontinence conservative treatment after RARP.
Edidence aquisition: A systematic literature review search using PubMed (Medline), Scopus, and Web of Science databases was performed in December 2019. PRISMA guidelines have been adopted. Population consisted of patients with urinary incontinence after RARP (P), conservative intervention was considered of interest (I). No comparator was considered mandatory (C). Outcomes of interest were the recovery of continence and quality of life (O).
Evidedence synthesis: Six studies were included. Four of them investigated the use of pelvic floor muscle training (PFMT). PFMT improved pelvic muscle strength. Continence recovery was faster when guided PFMT was adopted. Moreover, two studies tested the effect of solifenacin on urinary incontinence. One of them, a randomized clinical trial, failed to show shorter time to continence in solifenacin group compared to placebo.
Conclusions: The use of pads is associated with a detrimental effect on quality of life thus active treatments for UI post-RARP are warranted. PFMT has the main advantage to shorten the time for recovery. The use of solifenacin seems to not offer striking advantages in UI following RARP. Future studies should focus on testing the efficacy of these treatments when used after robotic vs. open radical prostatectomy.
机器人辅助根治性前列腺切除术(RARP)越来越受欢迎,成为最常见的根治性前列腺切除术技术。不幸的是,接受RARP治疗的患者中有不可忽视的比例出现尿失禁。我们旨在系统地回顾RARP术后尿失禁保守治疗的现有文献证据。证据获取:2019年12月,使用PubMed (Medline)、Scopus和Web of Science数据库进行了系统的文献综述检索。PRISMA准则已经通过。人群由RARP后尿失禁的患者组成(P),保守干预被认为是有意义的(I)。没有比较者被认为是强制性的(C)。感兴趣的结果是失禁的恢复和生活质量(O)。证据综合:包括6项研究。其中四个研究了盆底肌肉训练(PFMT)的使用。PFMT改善骨盆肌肉力量。采用引导式PFMT后,尿失禁恢复较快。此外,两项研究测试了索利那新对尿失禁的影响。其中一项随机临床试验,未能显示索利那新组与安慰剂组相比,尿失禁时间更短。结论:尿垫的使用与生活质量的不利影响有关,因此对rarp后尿失禁的积极治疗是必要的。PFMT的主要优点是缩短恢复时间。使用索利那新在RARP后的UI中似乎没有显著的优势。未来的研究应该集中在测试机器人与开放式根治性前列腺切除术后使用这些治疗方法的疗效。
期刊介绍:
The journal Minerva Urologica e Nefrologica publishes scientific papers on nephrology and urology. Manuscripts may be submitted in the form of Minerva opinion editorials, editorial comments, original articles, video illustrated articles, review articles and letters to the Editor.