Increase of sentinel lymph node melanoma staging in The Netherlands; still room and need for further improvement.

IF 1 Q4 ONCOLOGY

Melanoma Management Pub Date : 2020-03-30 DOI:10.2217/mmt-2019-0018

Eric A Deckers, Marieke Wj Louwman, Schelto Kruijff, Harald J Hoekstra

引用次数: 5

Abstract

Aim: To investigate implementation of the seventh American Joint Committee on Cancer melanoma staging with sentinel lymph node biopsy (SLNB) and associations with socioeconomic status (SES).

Patients & methods: Data from The Netherlands Cancer Registry on patient and tumor characteristics were analyzed for all stage IB-II melanoma cases diagnosed 2010-2016, along with SES data from The Netherlands Institute for Social Research.

Results: The proportion of SLNB-staged patients increased from 40% to 65% (p < 0.001). Multivariate analysis showed that being female, elderly, or having head-and-neck disease reduced the likelihood of SLNB staging.

Conclusion: SLNB staging increased by 25% during the study period but lagged among elderly patients and those with head-and-neck melanoma. In The Netherlands, SES no longer affects SLNB staging performance.

Abstract Image

查看原文本刊更多论文

荷兰前哨淋巴结黑色素瘤分期增加;仍有进一步改进的空间和需要。

目的:调查第七届美国癌症黑色素瘤前哨淋巴结活检(SLNB)分期联合委员会的实施情况及其与社会经济地位(SES)的关系。患者和方法:分析了荷兰癌症登记处2010-2016年诊断的所有IB-II期黑色素瘤病例的患者和肿瘤特征数据，以及荷兰社会研究所的SES数据。结果:SLNB分期患者比例从40%增加到65% (p)。结论:研究期间SLNB分期增加了25%，但在老年患者和头颈部黑色素瘤患者中滞后。在荷兰，SES不再影响SLNB分期性能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Melanoma Management ONCOLOGY-

CiteScore

5.10

自引率

0.00%

发文量

审稿时长

13 weeks

期刊介绍： Skin cancer is on the rise. According to the World Health Organization, 132,000 melanoma skin cancers occur globally each year. While early-stage melanoma is usually relatively easy to treat, once disease spreads prognosis worsens considerably. Therefore, research into combating advanced-stage melanoma is a high priority. New and emerging therapies, such as monoclonal antibodies, B-RAF and KIT inhibitors, antiangiogenic agents and novel chemotherapy approaches hold promise for prolonging survival, but the search for a cure is ongoing. Melanoma Management publishes high-quality peer-reviewed articles on all aspects of melanoma, from prevention to diagnosis and from treatment of early-stage disease to late-stage melanoma and metastasis. The journal presents the latest research findings in melanoma research and treatment, together with authoritative reviews, cutting-edge editorials and perspectives that highlight hot topics and controversy in the field. Independent drug evaluations assess newly approved medications and their role in clinical practice. Key topics covered include: Risk factors, prevention and sun safety education Diagnosis, staging and grading Surgical excision of melanoma lesions Sentinel lymph node biopsy Biological therapies, including immunotherapy and vaccination Novel chemotherapy options Treatment of metastasis Prevention of recurrence Patient care and quality of life.