A Review on the Etiology and Management of Pediatric Traumatic Spinal Cord Injuries.

Advanced Journal of Emergency Medicine Pub Date : 2019-10-10 eCollection Date: 2020-01-01 DOI:10.22114/ajem.v0i0.256
Amira Benmelouka, Laila Salah Shamseldin, Anas Zakarya Nourelden, Ahmed Negida
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Abstract

Context: Pediatric traumatic spinal cord injury (SCI) is an uncommon presentation in the emergency department. Severe injuries are associated with devastating outcomes and complications, resulting in high costs to both the society and the economic system.

Evidence acquisition: The data on pediatric traumatic spinal cord injuries has been narratively reviewed.

Results: Pediatric SCI is a life-threatening emergency leading to serious outcomes and high mortality in children if not managed promptly. Pediatric SCI can impose many challenges to neurosurgeons and caregivers because of the lack of large studies with high evidence level and specific guidelines in terms of diagnosis, initial management and of in-hospital treatment options. Several novel potential treatment options for SCI have been developed and are currently under investigation. However, research studies into this field have been limited by the ethical and methodological challenges.

Conclusion: Future research is needed to investigate the safety and efficacy of the recent uprising neurodegenerative techniques in SCI population. Owing to the current limitations, there is a need to develop novel trial methodologies that can overcome the current methodological and ethical limitations.

小儿外伤性脊髓损伤的病因和处理综述。
背景:小儿外伤性脊髓损伤(SCI)在急诊科并不常见。严重的损伤会导致灾难性的后果和并发症,给社会和经济系统带来高昂的成本:结果:结果:小儿脊髓损伤是一种危及生命的急症,如果处理不及时,会导致严重后果和高死亡率。小儿 SCI 会给神经外科医生和护理人员带来许多挑战,因为在诊断、初始管理和院内治疗方案方面缺乏高证据级别的大型研究和具体指南。针对 SCI 的几种新的潜在治疗方案已经开发出来,目前正在研究之中。然而,该领域的研究因伦理和方法上的挑战而受到限制:结论:未来的研究需要调查最近在 SCI 患者中兴起的神经退行性技术的安全性和有效性。由于目前的局限性,有必要开发新的试验方法,以克服目前在方法和伦理方面的局限性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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