Efficacy of modified radical prostatectomy technique for recovery of urinary incontinence in high-grade prostate cancer.

Q1 Medicine

Minerva Urologica E Nefrologica Pub Date : 2020-10-01 Epub Date: 2020-04-16 DOI:10.23736/S0393-2249.20.03633-4

Jae W Chung, Sang W Kim, Ho W Kang, Yun S Ha, Seock H Choi, Jun N Lee, Bum S Kim, Hyun T Kim, Tae H Kim, Ghil S Yoon, Tae G Kwon, Sung K Chung, Eun S Yoo

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引用次数: 0

Abstract

Background: This study was conducted to evaluate predictive factors of urinary continence recovery after radical prostatectomy (RP) for high-grade prostate cancer (PCa).

Methods: A total of 241 patients with high-grade (Gleason Score 8 or 9) PCa who underwent RP in a single Korean center between January 2011 and May 2018 were retrospectively reviewed. Urinary continence was defined as no pads use. Urinary continence was evaluated at 1, 3, 6, and 12 months after RP. Univariate and multivariate analyses were performed to determine the predictive factors of urinary continence recovery after RP.

Results: The mean age was 67.6±6.4 years, and the mean PSA was 18.7±21.1 ng/dL. A total of 197 (81.7%) patients underwent nerve-sparing RP, and 198 patients (82.2%) were continent 1 year after RP. Multivariate analysis showed that the age (odds ratio [OR]=1.091 [1.015-1.172], P=0.018), Body Mass Index (BMI) (OR=1.227 [1.057-1.424], P=0.007), and modified surgical technique (OR=0.109 [0.044-0.267], P<0.001) were independent factors for predicting urinary continence recovery after RP.

Conclusions: Younger age, low BMI, and modified surgery were independent predictors of urinary continence recovery after RP in patients with high-grade PCa. These findings may help surgeons to give pre- and postoperative advice to patients with high-grade PCa about urinary continence recovery after RP.

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改良根治性前列腺切除术对恢复高级别前列腺癌患者尿失禁的疗效。

背景：本研究旨在评估高位前列腺癌（PCa）根治性前列腺切除术（RP）后尿失禁恢复的预测因素：本研究旨在评估高级别前列腺癌（PCa）根治性前列腺切除术（RP）后尿失禁恢复的预测因素：方法：回顾性研究了 2011 年 1 月至 2018 年 5 月期间在韩国一家中心接受前列腺癌根治术（RP）的 241 例高级别（格雷森评分 8 分或 9 分）PCa 患者。尿失禁定义为未使用尿垫。在 RP 术后 1、3、6 和 12 个月对尿失禁情况进行评估。进行了单变量和多变量分析，以确定 RP 术后尿失禁恢复的预测因素：平均年龄为 67.6±6.4 岁，平均 PSA 为 18.7±21.1 ng/dL。共有197名患者（81.7%）接受了保留神经的RP术，198名患者（82.2%）在RP术后1年仍能排尿。多变量分析显示，年龄（几率比 [OR]=1.091 [1.015-1.172]，P=0.018）、体重指数（BMI）（OR=1.227 [1.057-1.424]，P=0.007）和改良手术技术（OR=0.109 [0.044-0.267]，PConclusions：年轻、低体重指数和改良手术是高级别PCa患者RP术后尿失禁恢复的独立预测因素。这些发现可能有助于外科医生向高级别PCa患者提供关于RP术后排尿功能恢复的术前和术后建议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Minerva Urologica E Nefrologica UROLOGY & NEPHROLOGY-

CiteScore

5.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The journal Minerva Urologica e Nefrologica publishes scientific papers on nephrology and urology. Manuscripts may be submitted in the form of Minerva opinion editorials, editorial comments, original articles, video illustrated articles, review articles and letters to the Editor.