Sepsis prevalence among patients with suspected infection in emergency department: a multicenter prospective cohort study.

IF 3.1 4区医学 Q1 EMERGENCY MEDICINE

European Journal of Emergency Medicine Pub Date : 2020-10-01 DOI:10.1097/MEJ.0000000000000689

Mathieu Oberlin, Frederic Balen, Lionel Bertrand, Noellie Chapeau, Bastien San Cirilo, Emmanuelle Ruols, Thomas Vandercamere, Clement Souchaud, Jean François Guedj, Bertille Konan, Alice Duval, Sebastien Mur, Anne Sophie Specia-Fajolles, Marie Salles, Eric Boullenger, Olivier Vuillot, Xavier Bobbia

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引用次数: 3

Abstract

Objective: In the emergency department (ED), the early identification of patients suspected of infection is a challenge for emergency physicians. Sepsis prevalence among patients with suspected infection in the ED remains uncertain. Our objective was to determine how many cases of sepsis occurred among patients with suspected infections in the ED.

Methods: This multi-center, prospective, observational study was conducted in 19 EDs in France. For 1 week, all consecutive ED patients with suspected infection (according to the emergency physician) were included. The primary endpoint was the prevalence of sepsis in the ED according to the 'sepsis-3' definition. Secondary endpoints involved comparisons among patients with and without sepsis.

Results: During the study period, 13 904 patients were screened; 494 (3.6%) consulted for suspected infection and were included in the study. Among them, 172 patients [39%, 95% confidence interval (CI) (34-44)] were diagnosed with sepsis. The total hospital mortality for patients with a suspected infection was 4.7% and the hospital mortality for sepsis patients was 9.9%.

Conclusion: In the ED, among patients with a suspected infection, the prevalence of sepsis as per the 'sepsis-3' definition was 39% [95% CI (34-44)].

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急诊疑似感染患者的脓毒症患病率:一项多中心前瞻性队列研究

目的:在急诊科(ED)，早期识别疑似感染患者是急诊科医师面临的挑战。在急诊科疑似感染的患者中，脓毒症的患病率仍不确定。我们的目的是确定急诊疑似感染患者中脓毒症的发生率。方法:这项多中心、前瞻性、观察性研究在法国的19个急诊中进行。在1周内，所有疑似感染的连续ED患者(根据急诊医生)被纳入。根据“脓毒症-3”的定义，主要终点是ED中脓毒症的患病率。次要终点包括脓毒症患者和非脓毒症患者的比较。结果:研究期间共筛查13 904例患者;494例(3.6%)因疑似感染就诊并纳入研究。其中172例[39%，95%可信区间(CI)(34-44)]被诊断为败血症。疑似感染患者的住院总死亡率为4.7%，败血症患者的住院总死亡率为9.9%。结论:在急诊科中，疑似感染的患者中，根据“脓毒症-3”定义的脓毒症患病率为39% [95% CI(34-44)]。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Emergency Medicine 医学-急救医学

CiteScore

3.60

自引率

27.30%

发文量

180

审稿时长

6-12 weeks

期刊介绍： The European Journal of Emergency Medicine is the official journal of the European Society for Emergency Medicine. It is devoted to serving the European emergency medicine community and to promoting European standards of training, diagnosis and care in this rapidly growing field. Published bimonthly, the Journal offers original papers on all aspects of acute injury and sudden illness, including: emergency medicine, anaesthesiology, cardiology, disaster medicine, intensive care, internal medicine, orthopaedics, paediatrics, toxicology and trauma care. It addresses issues on the organization of emergency services in hospitals and in the community and examines postgraduate training from European and global perspectives. The Journal also publishes papers focusing on the different models of emergency healthcare delivery in Europe and beyond. With a multidisciplinary approach, the European Journal of Emergency Medicine publishes scientific research, topical reviews, news of meetings and events of interest to the emergency medicine community. Submitted articles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.