Higher Odds of Type 2 Diabetes for Some Blood Groups.

IF 1.3 4区医学 Q4 GENETICS & HEREDITY

Public Health Genomics Pub Date : 2020-01-01 Epub Date: 2020-04-06 DOI:10.1159/000506294

Jafar Navabi, Seyed Mohammad Navabi, Niloufar Hemmati, Zahra Shaahmadi, Abbas Aghaei

{"title":"Higher Odds of Type 2 Diabetes for Some Blood Groups.","authors":"Jafar Navabi, Seyed Mohammad Navabi, Niloufar Hemmati, Zahra Shaahmadi, Abbas Aghaei","doi":"10.1159/000506294","DOIUrl":null,"url":null,"abstract":"Background: Diabetes is one of the most common metabolic diseases in humans that cause disruption in glucose and fat metabolism. The determination of the ABO blood group system is hereditary and both diabetes and blood groups have a genetic basis.Objectives: The aim of this study was to investigate the odds of type 2 diabetes for some blood groups.Methods: This case-control study was conducted in hospitals of Kermanshah in 2018. The case group consisted of patients with diabetes admitted to hospital and the control group of nondiabetic patients hospitalized in the surgical ward. Information such as age, sex, BMI, family history of diabetes and blood group is collected and analyzed by the univariate and multivariate logistic regression method.Results: A total of 750 patients were enrolled in this study. The number of participants in both groups was 375. The average ages of the participants were 50.51 and 51.62 years, respectively. 67.5% of the patients in the case group were female in comparison with 73.6% of those in the control group. The value of Rh+ in the case and control groups was 94.4 and 93.6%, respectively (p = 0.645). The chance of having diabetes for patients with blood group A was 76% higher than for those with blood group O (p = 0.006).Conclusion: According to the results of this study, the odds of type 2 diabetes for people in blood group A was higher than for those in other blood groups. It is recommended that blood group A be considered as a risk factor in the screening of type 2 diabetes.","PeriodicalId":49650,"journal":{"name":"Public Health Genomics","volume":"23 1-2","pages":"37-41"},"PeriodicalIF":1.3000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000506294","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Public Health Genomics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000506294","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/4/6 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"GENETICS & HEREDITY","Score":null,"Total":0}

引用次数: 2

Abstract

Background: Diabetes is one of the most common metabolic diseases in humans that cause disruption in glucose and fat metabolism. The determination of the ABO blood group system is hereditary and both diabetes and blood groups have a genetic basis.

Objectives: The aim of this study was to investigate the odds of type 2 diabetes for some blood groups.

Methods: This case-control study was conducted in hospitals of Kermanshah in 2018. The case group consisted of patients with diabetes admitted to hospital and the control group of nondiabetic patients hospitalized in the surgical ward. Information such as age, sex, BMI, family history of diabetes and blood group is collected and analyzed by the univariate and multivariate logistic regression method.

Results: A total of 750 patients were enrolled in this study. The number of participants in both groups was 375. The average ages of the participants were 50.51 and 51.62 years, respectively. 67.5% of the patients in the case group were female in comparison with 73.6% of those in the control group. The value of Rh+ in the case and control groups was 94.4 and 93.6%, respectively (p = 0.645). The chance of having diabetes for patients with blood group A was 76% higher than for those with blood group O (p = 0.006).

Conclusion: According to the results of this study, the odds of type 2 diabetes for people in blood group A was higher than for those in other blood groups. It is recommended that blood group A be considered as a risk factor in the screening of type 2 diabetes.

查看原文本刊更多论文

某些血型的人患2型糖尿病的几率更高。

背景:糖尿病是人类最常见的代谢性疾病之一，可导致葡萄糖和脂肪代谢紊乱。ABO血型系统的决定是遗传的，糖尿病和血型都有遗传基础。目的:本研究的目的是调查某些血型的人患2型糖尿病的几率。方法:本病例-对照研究于2018年在克尔曼沙阿医院进行。病例组为住院的糖尿病患者，对照组为外科病房的非糖尿病患者。收集年龄、性别、BMI、糖尿病家族史、血型等信息，采用单因素和多因素logistic回归方法进行分析。结果:本研究共纳入750例患者。两组的参与者人数都是375人。参与者的平均年龄分别为50.51岁和51.62岁。病例组中女性占67.5%，对照组中女性占73.6%。病例组和对照组的Rh+值分别为94.4和93.6% (p = 0.645)。A型血患者患糖尿病的几率比O型血患者高76% (p = 0.006)。结论:根据这项研究的结果，A血型的人患2型糖尿病的几率高于其他血型的人。建议将A型血作为筛查2型糖尿病的一个危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Public Health Genomics 医学-公共卫生、环境卫生与职业卫生

CiteScore

2.90

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： ''Public Health Genomics'' is the leading international journal focusing on the timely translation of genome-based knowledge and technologies into public health, health policies, and healthcare as a whole. This peer-reviewed journal is a bimonthly forum featuring original papers, reviews, short communications, and policy statements. It is supplemented by topic-specific issues providing a comprehensive, holistic and ''all-inclusive'' picture of the chosen subject. Multidisciplinary in scope, it combines theoretical and empirical work from a range of disciplines, notably public health, molecular and medical sciences, the humanities and social sciences. In so doing, it also takes into account rapid scientific advances from fields such as systems biology, microbiomics, epigenomics or information and communication technologies as well as the hight potential of ''big data'' for public health.