Multicentre Covariate Adjustment Analysis of Short-Term and 5-Year Outcomes after Endovascular Repair according to Sex.

Surgery Research and Practice Pub Date : 2020-03-09 eCollection Date: 2020-01-01 DOI:10.1155/2020/8970759

Bibombe P Mwipatayi, Rebekah L W Tan, Joseph Faraj, Ali Daneshmand, Olufemi Oshin, Nishath Altaf, Shannon D Thomas, Patrik J Tosenovsky, Jackie Wong, Vikram Vijayan, Anthony J Freeman, Sally A Burrows

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引用次数: 1

Abstract

Background: Several studies have reported worse outcomes in women compared to men after endovascular aneurysm repair (EVAR). This study aimed to evaluate sex-specific short-term and 5-year outcomes after EVAR.

Methods: A total of 409 consecutive patients underwent elective EVAR from 2004 to 2017 at two tertiary hospitals in Western Australia. Baseline, intraoperative, and postoperative variables were examined retrospectively according to sex. The primary outcome was 30-day mortality (death within 30 days after EVAR). Secondary outcomes were 30-day composite endpoint, length of stay after EVAR, 5-year survival, freedom from reintervention, residual aneurysm size after EVAR, and major adverse event rate at 5-year follow-up.

Results: A cohort of 409 patients, comprising 57 women (14%) and 352 men (86%), was analysed. Female patients were older (median age, 76.8 versus 73.5 years, p=0.017). Male patients were more likely to be past smokers (40.9% versus 22.8%, p=0.017). Male patients were more likely to be past smokers (40.9% versus 22.8%, p=0.017). Male patients were more likely to be past smokers (40.9% versus 22.8%, p=0.017). Male patients were more likely to be past smokers (40.9% versus 22.8%, p=0.017). Male patients were more likely to be past smokers (40.9% versus 22.8%, p=0.017). Male patients were more likely to be past smokers (40.9% versus 22.8%, p=0.017). Male patients were more likely to be past smokers (40.9% versus 22.8%.

Conclusion: This study found no significant differences in 30-day and 5-year outcomes between female and male patients treated with EVAR, implying that EVAR remains a safe treatment choice for female patients.

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不同性别血管内修复术后短期和5年预后的多中心协变量调整分析。

背景:一些研究报道了血管内动脉瘤修复(EVAR)后女性的预后比男性差。本研究旨在评估EVAR术后性别特异性的短期和5年预后。方法:2004年至2017年，在西澳大利亚州的两家三级医院共连续409例患者接受了选择性EVAR。根据性别回顾性检查基线、术中和术后变量。主要终点为30天死亡率(EVAR后30天内死亡)。次要终点为30天综合终点、EVAR术后住院时间、5年生存率、无再干预、EVAR术后残留动脉瘤大小、5年随访时主要不良事件发生率。结果:共纳入409例患者，其中女性57例(14%)，男性352例(86%)。女性患者年龄较大(中位年龄76.8岁对73.5岁，p=0.017)。男性患者更有可能是过去的吸烟者(40.9%比22.8%，p=0.017)。男性患者更有可能是过去的吸烟者(40.9%比22.8%，p=0.017)。男性患者更有可能是过去的吸烟者(40.9%比22.8%，p=0.017)。男性患者更有可能是过去的吸烟者(40.9%比22.8%，p=0.017)。男性患者更有可能是过去的吸烟者(40.9%比22.8%，p=0.017)。男性患者更有可能是过去的吸烟者(40.9%比22.8%，p=0.017)。男性患者更有可能是过去的吸烟者(40.9%对22.8%)。结论:本研究发现，女性和男性EVAR治疗患者的30天和5年预后无显著差异，这意味着EVAR仍然是女性患者的安全治疗选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Surgery Research and Practice

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期刊介绍： Surgery Research and Practice is a peer-reviewed, Open Access journal that provides a forum for surgeons and the surgical research community. The journal publishes original research articles, review articles, and clinical studies focusing on clinical and laboratory research relevant to surgical practice and teaching, with an emphasis on findings directly affecting surgical management.