Scenario of the Treatment of Arthritis with Natural Products.

IF 4.2 Q3 Pharmacology, Toxicology and Pharmaceutics

Recent patents on inflammation & allergy drug discovery Pub Date : 2020-01-01 DOI:10.2174/1872213X14666200228103001

Fernanda C M Gallotti, Mairim R Serafini, Sara M Thomazzi

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引用次数: 2

Abstract

Background: Conventional treatments of arthritis use toxic and poorly tolerated drugs. Therefore, natural products are an alternative because they are important sources of bioactive substances with therapeutic potential.

Objective: To perform synthesis of patent applications associated with the use of natural products in the technological development of the invention for use in treating arthritis.

Methods: The search for patents was conducted using the following databases of World Intellectual Property Organization (WIPO), European Patent Office (EPO, Espacenet), United States Patents and Trademark Office (USPTO) and National Institute of Intellectual Property (INPI) using as keywords - arthritis, treatment and the International Patent Classification (IPC) A61K36 / 00.

Results: A total of 617 patents related to the subject were registered in the period available in patents databases during the study period from the years 2005 to 2017, of which 44 were analyzed based on the established inclusion criteria. The most important countries for protecting these inventions were China, followed by the United States of America, the Republic of Korea and Japan. As for the typology of depositors, that were identified by Educational Institutions and Public Institutes of Research (IEIPP) and Companies and Private Research Institutes (EIPP).

Conclusion: The analysis of patents made it possible to characterize the natural products used in the treatment of arthritis, with emphasis on botanical extracts (71%), as a single component, as well as in association with other botanical extracts, isolated compounds and minerals.

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用天然产品治疗关节炎的情景。

背景:传统的关节炎治疗使用毒性和耐受性差的药物。因此，天然产品是一种替代品，因为它们是具有治疗潜力的生物活性物质的重要来源。目的:在本发明用于治疗关节炎的技术开发中，对与天然产物使用相关的专利申请进行综合。方法:采用世界知识产权组织(WIPO)、欧洲专利局(EPO, Espacenet)、美国专利商标局(USPTO)和美国国家知识产权局(INPI)的数据库进行专利检索，检索关键词为关节炎、治疗以及国际专利分类(IPC) A61K36 / 00。结果:2005 - 2017年研究期间，专利数据库共登记了与该课题相关的专利617件，其中44件根据建立的纳入标准进行了分析。保护这些发明最重要的国家是中国，其次是美利坚合众国、大韩民国和日本。至于存款人的类型，由教育机构和公共研究所(IEIPP)以及公司和私人研究所(EIPP)确定。结论:对专利的分析使得表征用于关节炎治疗的天然产品成为可能，重点是植物提取物(71%)，作为单一成分，以及与其他植物提取物，分离化合物和矿物质相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Recent patents on inflammation & allergy drug discovery PHARMACOLOGY & PHARMACY-

CiteScore

3.90

自引率

0.00%

发文量

期刊介绍： Recent Patents on Inflammation & Allergy Drug Discovery publishes review articles by experts on recent patents in the field of inflammation and allergy drug discovery e.g. on novel bioactive compounds, analogs and targets. A selection of important and recent patents in the field is also included in the journal. The journal is essential reading for all researchers involved in inflammation and allergy drug design and discovery.