Systemic immune response after open tension-free inguinal hernia repair under different anesthetic alternatives: a prospective comparative study.

IF 0.4 Q4 SURGERY

Giornale di Chirurgia Pub Date : 2020-01-01

D Symeonidis, A Diamantis, I Baloyiannis, G Tzovaras, K Tepetes

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引用次数: 0

Abstract

Purpose: The purpose of the present study was a comparison of the systemic inflammatory response intensity through the estimation of C- reactive protein and albumin levels before and after open tension free inguinal hernia repair performed under different anesthetic alternatives.

Patients and methods: Totally, 125 inguinal hernia patients scheduled for unilateral primary open tension free inguinal repair unRomader local (50 patients), spinal (50 patients) and general anesthesia (25 patients) have been included in this prospective study.

Results: The group of local anesthesia was associated with the higher postoperative serum levels of albumin compared to the group of general anesthesia (P 0.013). Local anesthesia was also associated with higher postoperative serum albumin levels compared to regional anesthesia but however the difference was not statistically significant (P 0.282). The group of local anesthesia was also associated with the lower postoperative levels of CRP compared to the regional (P 0.0094) and general anesthesia (P 0.0009) groups.

Conclusion: Local anesthesia proved superior to regional or general anesthesia for open tension free inguinal hernia repair in the given patient sample from the standpoint of the inflammatory and acute phase response.

本刊更多论文

不同麻醉方案下开放式无张力腹股沟疝修补术后的全身免疫反应:一项前瞻性比较研究。

目的:本研究的目的是通过评估不同麻醉方案下开放式无张力腹股沟疝修补术前后的C反应蛋白和白蛋白水平，比较全身炎症反应强度。患者和方法:本前瞻性研究共纳入125例腹股沟疝患者，计划在romader局部(50例)、脊柱(50例)和全身麻醉(25例)下进行单侧开放式无张力腹股沟修补术。结果:局麻组术后血清白蛋白水平高于全麻组(P < 0.013)。与区域麻醉相比，局部麻醉术后血清白蛋白水平也较高，但差异无统计学意义(P 0.282)。与局部麻醉组(P 0.0094)和全身麻醉组(P 0.0009)相比，局麻组术后CRP水平也较低。结论:从炎症和急性期反应的角度来看，局麻优于区域或全麻，适用于开放式无张力腹股沟疝修补术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Giornale di Chirurgia SURGERY-

CiteScore

1.10

自引率

0.00%

发文量

期刊介绍： Il Giornale di Chirurgia pubblica contributi che propongono le diverse tecniche su patologia chirurgiche di attualità. Pubblica articoli originali, casistica clinica, metodi, tecniche, terapia farmacologica pre-operatoria e post-chirurgica, ed articoli inerenti la descrizione di tecniche chirurgiche.