Correlation between healing type of lesion and recurrence in gastric neoplastic lesions after endoscopic submucosal dissection.

Jae Hwang Cha, Jin Seok Jang
{"title":"Correlation between healing type of lesion and recurrence in gastric neoplastic lesions after endoscopic submucosal dissection.","authors":"Jae Hwang Cha,&nbsp;Jin Seok Jang","doi":"10.5152/tjg.2020.18764","DOIUrl":null,"url":null,"abstract":"<p><strong>Background/aims: </strong>To date, there are few reports on the clinical association between healing pattern of lesion and local recurrence after endoscopic resection (ER). We examined the risk factors associated with local recurrence after endoscopic submucosal dissection (ESD) and the correlation between healing type of lesion and recurrence.</p><p><strong>Materials and methods: </strong>We retrospectively analyzed medical records of 293 patients who underwent ESD of early gastric cancer or gastric adenoma between April 2010 and January 2012. We analyzed the relationship among factors such as age, location of lesion, size, pathologic diagnosis, presence of Helicobacter pylori (H. pylori), and healing types of ulcers in patients with local recurrence through follow-up endoscopic surveillance (1, 6, and 12 months after ESD).</p><p><strong>Results: </strong>We analyzed 141 patients except for patients who had not undergone surveillance endoscopy, H. pylori test, and ambiguous healing patterns. There were no significant correlations between local recurrences concerning sex, age, tumor size, location, and pathologic diagnosis. When the healing type of the ulcer was divided into hypertrophic polypoid type (9 cases (6.4%)), scar type (122 cases (86.5%)), and nodular type (10 cases (7.1%)), the scar type was found to be most common. A total of eight patients (5.7%) developed local recurrence, of which five were of nodular type and statistically significant (p=0.000).</p><p><strong>Conclusion: </strong>The most common type of ulcer healing was scar type after ESD, but nodular type was associated with local recurrence. When we perform follow-up endoscopy after ESD, we should pay attention to the lesion that has nodular change of mucosal surface.</p>","PeriodicalId":518528,"journal":{"name":"The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology","volume":" ","pages":"36-41"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075678/pdf/tjg-31-1-36.pdf","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5152/tjg.2020.18764","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6

Abstract

Background/aims: To date, there are few reports on the clinical association between healing pattern of lesion and local recurrence after endoscopic resection (ER). We examined the risk factors associated with local recurrence after endoscopic submucosal dissection (ESD) and the correlation between healing type of lesion and recurrence.

Materials and methods: We retrospectively analyzed medical records of 293 patients who underwent ESD of early gastric cancer or gastric adenoma between April 2010 and January 2012. We analyzed the relationship among factors such as age, location of lesion, size, pathologic diagnosis, presence of Helicobacter pylori (H. pylori), and healing types of ulcers in patients with local recurrence through follow-up endoscopic surveillance (1, 6, and 12 months after ESD).

Results: We analyzed 141 patients except for patients who had not undergone surveillance endoscopy, H. pylori test, and ambiguous healing patterns. There were no significant correlations between local recurrences concerning sex, age, tumor size, location, and pathologic diagnosis. When the healing type of the ulcer was divided into hypertrophic polypoid type (9 cases (6.4%)), scar type (122 cases (86.5%)), and nodular type (10 cases (7.1%)), the scar type was found to be most common. A total of eight patients (5.7%) developed local recurrence, of which five were of nodular type and statistically significant (p=0.000).

Conclusion: The most common type of ulcer healing was scar type after ESD, but nodular type was associated with local recurrence. When we perform follow-up endoscopy after ESD, we should pay attention to the lesion that has nodular change of mucosal surface.

胃镜下粘膜下剥离术后胃肿瘤病变愈合类型与复发的关系。
背景/目的:迄今为止,很少有关于内镜切除(ER)后病变愈合方式与局部复发的临床关联的报道。我们研究了内镜下粘膜下剥离(ESD)术后局部复发的相关危险因素以及病变愈合类型与复发的关系。材料与方法:回顾性分析2010年4月至2012年1月间293例早期胃癌或胃腺瘤行ESD治疗的病例。我们通过内镜随访(ESD术后1、6、12个月)对局部复发患者的年龄、病变部位、大小、病理诊断、是否存在幽门螺杆菌(h.p ylori)、溃疡愈合类型等因素进行分析。结果:我们分析了141例患者,但未接受内窥镜检查、幽门螺旋杆菌检查和不明确愈合模式的患者除外。局部复发与性别、年龄、肿瘤大小、部位和病理诊断无显著相关性。将溃疡的愈合类型分为增生性息肉型(9例(6.4%))、瘢痕型(122例(86.5%))和结节型(10例(7.1%)),瘢痕型最为常见。局部复发8例(5.7%),其中结节型5例,差异有统计学意义(p=0.000)。结论:ESD术后溃疡愈合以瘢痕型为主,结节型与局部复发相关。ESD术后随访内镜检查时,应注意有无粘膜表面有结节性改变的病变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信