Low-Level Radiofrequency Exposure Does Not Induce Changes in MSC Biology: An in vitro Study for the Prevention of NIR-Related Damage.

IF 1.7 Q4 CELL BIOLOGY
Stem Cells and Cloning-Advances and Applications Pub Date : 2019-12-18 eCollection Date: 2019-01-01 DOI:10.2147/SCCAA.S204166
Nicola Alessio, Elisa Santoro, Tiziana Squillaro, Domenico Aprile, Massimo Briccola, Paolo Giubbini, Raffaella Marchesani, Maria Rosaria Muoio, Monica Lamberti
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引用次数: 2

Abstract

Background: The ubiquitous diffusion of radiofrequency (RF) radiation across human living environments has attracted the attention of scientists. Though the adverse health effects of RF exposure remain debatable, it has been reported that the interaction of such radiation with biological macromolecular structures can be deleterious for stem cells, inducing impairment of their main functions involving self-renewal and differentiation.

Purpose: The purpose of this study was to determine whether exposure to RF of 169 megahertz (MHz) that is part of very high radiofrequency (VHF) range 30-300 MHz, could cause damage to stem cells by inducing senescence and loss of regenerative and DNA repair capacity.

Methods: The study was conducted on mesenchymal stromal cells (MSCs) containing a subpopulation of stem cells. The MSCs were exposed to RFs of 169 MHz administered via an open meter 2G "Smart Meter" for different durations of time.

Result: We did not observe modifications in MSC biology as a result of the RF exposure conducted in our experiments.

Conclusion: We concluded that MSCs are insensitive to RF radiation exposure at 169 MHz for various time intervals, including longer durations.

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低水平射频暴露不会诱导间充质干细胞生物学变化:一项预防nir相关损伤的体外研究。
背景:射频辐射在人类生活环境中无处不在的扩散引起了科学家们的关注。尽管射频暴露对健康的不利影响仍有争议,但据报道,这种辐射与生物大分子结构的相互作用可能对干细胞有害,导致其涉及自我更新和分化的主要功能受损。目的:本研究的目的是确定暴露于169兆赫(MHz)的射频(甚高频(VHF)范围30-300 MHz的一部分)是否会通过诱导衰老和再生和DNA修复能力的丧失而对干细胞造成损害。方法:对含有干细胞亚群的间充质基质细胞(MSCs)进行研究。MSCs通过2G“智能电表”在不同时间内暴露于169 MHz的射频辐射。结果:我们在实验中没有观察到射频暴露对MSC生物学的影响。结论:我们得出的结论是,MSCs对169 MHz的射频辐射暴露在不同的时间间隔(包括更长的持续时间)不敏感。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.50
自引率
0.00%
发文量
10
审稿时长
16 weeks
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