The Limited Roles of Autocatalysis and Enantiomeric Cross-Inhibition in Achieving Homochirality in Dilute Systems.

IF 1.9 4区物理与天体物理 Q2 BIOLOGY

Origins of Life and Evolution of Biospheres Pub Date : 2019-06-01 Epub Date: 2019-07-08 DOI:10.1007/s11084-019-09579-4

Axel Brandenburg

引用次数: 14

Abstract

To understand the effects of fluctuations on achieving homochirality, we employ a Monte-Carlo method where autocatalysis and enantiomeric cross-inhibition, as well as racemization and deracemization reactions are included. The results of earlier work either without autocatalysis or without cross-inhibition are reproduced. Bifurcation diagrams and the dependencies of the number of reaction steps on parameters are studied. In systems with 30,000 molecules, for example, up to a billion reaction steps may be needed to achieve homochirality without autocatalysis.

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自催化和对映体交叉抑制在稀体系中实现同手性中的有限作用。

为了了解波动对实现同手性的影响，我们采用蒙特卡罗方法，其中包括自催化和对映体交叉抑制，以及外消旋和去消旋反应。没有自催化或没有交叉抑制的早期工作的结果被复制。研究了分岔图和反应步数与参数的关系。例如，在具有30,000个分子的体系中，可能需要多达10亿个反应步骤才能在没有自催化的情况下实现同手性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Origins of Life and Evolution of Biospheres 生物-生物学

CiteScore

3.20

自引率

15.00%

发文量

审稿时长

>12 weeks

期刊介绍： The subject of the origin and early evolution of life is an inseparable part of the general discipline of Astrobiology. The journal Origins of Life and Evolution of Biospheres places special importance on the interconnection as well as the interdisciplinary nature of these fields, as is reflected in its subject coverage. While any scientific study which contributes to our understanding of the origins, evolution and distribution of life in the Universe is suitable for inclusion in the journal, some examples of important areas of interest are: prebiotic chemistry and the nature of Earth''s early environment, self-replicating and self-organizing systems, the theory of the RNA world and of other possible precursor systems, and the problem of the origin of the genetic code. Early evolution of life - as revealed by such techniques as the elucidation of biochemical pathways, molecular phylogeny, the study of Precambrian sediments and fossils and of major innovations in microbial evolution - forms a second focus. As a larger and more general context for these areas, Astrobiology refers to the origin and evolution of life in a cosmic setting, and includes interstellar chemistry, planetary atmospheres and habitable zones, the organic chemistry of comets, meteorites, asteroids and other small bodies, biological adaptation to extreme environments, life detection and related areas. Experimental papers, theoretical articles and authorative literature reviews are all appropriate forms for submission to the journal. In the coming years, Astrobiology will play an even greater role in defining the journal''s coverage and keeping Origins of Life and Evolution of Biospheres well-placed in this growing interdisciplinary field.