Surveillance imaging for metastasis in high-risk melanoma: importance in individualized patient care and survivorship.

IF 1 Q4 ONCOLOGY

Melanoma Management Pub Date : 2019-04-18 eCollection Date: 2019-03-01 DOI:10.2217/mmt-2019-0003

Morganna Freeman, Shachar Laks

引用次数: 0

Abstract

Most patients newly diagnosed with melanoma have early-stage disease considered of good prognosis. However, with a risk of recurrence, appropriate follow-up may include surveillance imaging for early relapse detection. Previously, surveillance imaging to detect recurrences was considered unjustified, given the lack of effective treatments. Now, systemic therapies have improved, and patients with low tumor burden may derive benefit from surveillance imaging. Despite this, controversy exists regarding the role of surveillance imaging in early-stage melanoma survivorship, in part reflected by the lack of consensus on specific imaging protocols and broad guidelines. This review discusses published evidence on surveillance imaging to detect metastasis in high-risk melanoma, the need for early recurrence detection and implications for value-based clinical decision-making, survivorship care and multidisciplinary patient management.

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高危黑色素瘤转移监测成像：对个体化患者护理和生存的重要性。

大多数新确诊的黑色素瘤患者属于早期疾病，预后良好。然而，由于存在复发风险，适当的随访可能包括监测成像以早期发现复发。以前，由于缺乏有效的治疗方法，人们认为监测成像以检测复发是不合理的。现在，系统性疗法有所改善，肿瘤负担较轻的患者可能会从监测成像中获益。尽管如此，关于监测成像在早期黑色素瘤存活率中的作用仍存在争议，部分原因是对具体的成像方案和广泛的指南缺乏共识。本综述将讨论已发表的有关监测成像检测高危黑色素瘤转移的证据、早期复发检测的必要性以及对基于价值的临床决策、生存期护理和多学科患者管理的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Melanoma Management ONCOLOGY-

CiteScore

5.10

自引率

0.00%

发文量

审稿时长

13 weeks

期刊介绍： Skin cancer is on the rise. According to the World Health Organization, 132,000 melanoma skin cancers occur globally each year. While early-stage melanoma is usually relatively easy to treat, once disease spreads prognosis worsens considerably. Therefore, research into combating advanced-stage melanoma is a high priority. New and emerging therapies, such as monoclonal antibodies, B-RAF and KIT inhibitors, antiangiogenic agents and novel chemotherapy approaches hold promise for prolonging survival, but the search for a cure is ongoing. Melanoma Management publishes high-quality peer-reviewed articles on all aspects of melanoma, from prevention to diagnosis and from treatment of early-stage disease to late-stage melanoma and metastasis. The journal presents the latest research findings in melanoma research and treatment, together with authoritative reviews, cutting-edge editorials and perspectives that highlight hot topics and controversy in the field. Independent drug evaluations assess newly approved medications and their role in clinical practice. Key topics covered include: Risk factors, prevention and sun safety education Diagnosis, staging and grading Surgical excision of melanoma lesions Sentinel lymph node biopsy Biological therapies, including immunotherapy and vaccination Novel chemotherapy options Treatment of metastasis Prevention of recurrence Patient care and quality of life.