A Novel Biomimetic Stimulator System for Neural Implant.

International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering Pub Date : 2019-03-01 Epub Date: 2019-05-20 DOI:10.1109/NER.2019.8716942

Po-Min Wang, Stanislav Culaclii, William Yang, Yan Long, Jonathan Massachi, Yi-Kai Lo, Wentai Liu

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引用次数: 3

Abstract

Electrical stimulation using non-periodic biomimetic stimulation pattern has been shown to be effective in various critical biomedical applications. However, the existing programmable stimulators that support this protocol are non-portable and have architectures that are not translatable to wearable or implantable applications. In this work, we present a 32-channel neural stimulator system based on an implantable System-On-Chip (SoC) that addresses these technological challenges. The system is designed to be portable, powered by a single battery, wirelessly controlled, and versatile to perform concurrent multi-channel stimulation with independent arbitrary waveforms. The experimental results demonstrate multi-channel stimulation mimicking electromyography (EMG) waveforms and randomly-spaced stimulation pulses mimicking neuronal firing patterns. This compact and highly flexible prototype can support various neuromodulation researches and animal studies and serves as a precursor for the development of the next generation implantable biomimetic stimulator.

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一种新型神经植入仿生刺激系统。

采用非周期仿生刺激模式的电刺激已被证明在各种关键的生物医学应用中是有效的。然而，现有的支持该协议的可编程刺激器是不可移植的，其架构不能翻译为可穿戴或植入式应用。在这项工作中，我们提出了一个基于植入式片上系统(SoC)的32通道神经刺激系统，以解决这些技术挑战。该系统具有便携性、单电池供电、无线控制、多功能，可同时执行独立任意波形的多通道刺激。实验结果表明，多通道刺激模拟肌电图(EMG)波形和随机间隔刺激脉冲模拟神经元放电模式。这种紧凑和高度灵活的原型可以支持各种神经调节研究和动物研究，并作为下一代植入式仿生刺激器开发的先驱。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering

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