Synthesis, characterization, and POM-protein interactions of a Fe-substituted Krebs-type Sandwich-tungstoantimonate.

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Monatshefte Fur Chemie Pub Date : 2019-01-01 Epub Date: 2019-04-29 DOI:10.1007/s00706-019-2381-5

Elias Tanuhadi, Ioannis Kampatsikas, Gerald Giester, Annette Rompel

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引用次数: 4

Abstract

Abstract: The novel iron-substituted Krebs-type polyoxotungstate (C₁₂N₄H₁₁)₄Na₂H₅[(Fe(H₂O)₃)₂((FeO₂)_0.5(WO₂)_0.5)₂(β-SbW₉O₃₃)₂] (Fe-1) has been synthesized using ortho-phenylenediamine (opda) as a precursor for the in situ formation of the counter cation 2,3-diaminophenazinium (C₁₂N₄H₁₁)⁺ (2,3-DAP). Fe-1 has been thoroughly characterized in the solid state by single-crystal X-ray diffraction (SXRD), powder X-ray diffraction (PXRD), IR spectroscopy, and elemental analysis as well as in solution by UV-Vis spectroscopy. The crystal structure of Fe-1 reveals π-π-interactions between the aromatic systems of the unconventional 2,3-DAP counter cation. POM-protein interaction studies using SDS-PAGE revealed a non-proteolytic behavior of Fe-1 towards Human Serum Albumin (HSA) as a model protein.

Graphical abstract:

Abstract Image

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铁取代Krebs型三明治钨锑酸盐的合成、表征和POM蛋白相互作用。

摘要：以邻苯二胺（opda）为前驱体，原位合成了新型铁取代的Krebs型聚氧化钨（C12N4H11）4Na2H5[（Fe（H2O）3）2（（（FeO2）0.5（WO2）0.5）2（β-SbW9O33）2]（Fe-1）。Fe-1在固体状态下通过单晶X射线衍射（SXRD）、粉末X-射线衍射（PXRD）、IR光谱和元素分析以及在溶液中通过UV-Vis光谱进行了彻底的表征。Fe-1的晶体结构揭示了非常规2,3-DAP反阳离子芳香体系之间的π-π相互作用。使用SDS-PAGE的POM蛋白相互作用研究揭示了Fe-1对作为模型蛋白的人血清白蛋白（HSA）的非蛋白水解行为。图形摘要：

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来源期刊

Monatshefte Fur Chemie 化学-化学综合

CiteScore

3.70

自引率

5.60%

发文量

116

审稿时长

3.3 months

期刊介绍： "Monatshefte für Chemie/Chemical Monthly" was originally conceived as an Austrian journal of chemistry. It has evolved into an international journal covering all branches of chemistry. Featuring the most recent advances in research in analytical chemistry, biochemistry, inorganic, medicinal, organic, physical, structural, and theoretical chemistry, Chemical Monthly publishes refereed original papers and a section entitled "Short Communications". Reviews, symposia in print, and issues devoted to special fields will also be considered.