Surgical treatment of concomitant severe heart disease and lung cancer.

Tiago Adrega, João Pedro Monteiro, Susana Lareiro, Miguel Guerra, Luís Vouga
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Abstract

The concomitant presentation of lung cancer and severe heart disease requiring intervention is a scenario that many clinicians have to face. Its common physiopathological substratum is unknown and it is believed that tobacco plays a role. From a surgical point of view, these patients pose various technical challenges and medical literature is scarce in providing solid answers. The aim of this report is to review our experience with cases undergoing combined surgical treatment of both heart disease and lung cancer, aiming to analyse patients' characteristics, operative technical considerations and related outcomes. A total of five patients were included, with two synchronous procedures, two cases with lung surgery being performed first and one case commenced with cardiac surgery. All cancers were non-small-cell lung carcinoma or carcinoid tumors and cardiac disease was mostly represented by severe aortic stenosis. Lobectomy was performed in two thirds of patients and minimally invasive techniques were used in 60% of the procedures. All valvular patients received a bioprosthesis. There was one immediate complication, with good recovery on follow-up, and there were no late events (median follow-up of 1,8 ±1,1 months). The analysis of these cases highlights the complex nature of these challenging patients and reinforces the importance of devoting efforts to offer the most suitable solutions for each scenario.

伴发严重心脏病和肺癌的外科治疗。
肺癌和严重心脏病同时出现需要干预的情况是许多临床医生不得不面对的。其共同的生理病理基础尚不清楚,人们认为烟草起了一定作用。从外科的角度来看,这些患者提出了各种技术挑战,医学文献很少提供可靠的答案。本报告的目的是回顾我们对心脏病和肺癌联合手术治疗的病例的经验,旨在分析患者的特点、手术技术注意事项和相关结果。共纳入5例患者,2例同步手术,2例首先进行肺手术,1例开始进行心脏手术。所有肿瘤均为非小细胞肺癌或类癌,心脏疾病以主动脉严重狭窄为主要表现。三分之二的患者进行了肺叶切除术,60%的手术采用了微创技术。所有瓣膜患者均接受生物假体。1例即刻并发症,随访恢复良好,无晚期事件(中位随访时间为1.8±1.1个月)。对这些病例的分析突出了这些具有挑战性的患者的复杂性,并强调了致力于为每种情况提供最合适解决方案的重要性。
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