Challenges in the Contemporary Management of Syphilis among Pregnant Women in New Orleans, LA.

Q2 Medicine

Infectious Diseases in Obstetrics and Gynecology Pub Date : 2019-02-13 eCollection Date: 2019-01-01 DOI:10.1155/2019/2613962

Irene A Stafford, Alexandra Berra, Charles G Minard, Virginia Fontenot, Rachel H Kopkin, Eliza Rodrigue, Charles M Roitsch, Martha W Rac, James B Hill

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引用次数: 0

Abstract

Objective: The aim of this retrospective review is to evaluate trends in the management of maternal and congenital syphilis (CS) in a tertiary care center in New Orleans, LA.

Study design: All cases of maternal and neonatal syphilis over a five year period at Touro Infirmary, New Orleans, LA, were identified using ICD-9/10 codes. Charts were reviewed for demographic and obstetrical variables, stage of syphilis at diagnosis, lab values, and treatment regimen. Newborn treatment and other outcomes were recorded.

Results: During the study period 106 infected mother-baby pairs were identified. Of these, 73 charts are available for review. 41% (n = 30) of women received inadequate therapy according to their stage of disease. 9% of newborns (n = 6) were found to be symptomatic for CS; however, only 83.3% of these were admitted to the neonatal intensive care unit. Only 20% (n = 6) of infants were adequately treated with an extended penicillin regimen if the mother was not adequately treated. Furthermore, only 63.0% of newborns had a nontreponemal titer performed.

Conclusion: With rising rates of CS, strict adherence to the 2015 CDC guidelines for treatment of syphilis must be maintained.

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洛杉矶新奥尔良市孕妇梅毒的当代管理挑战。

研究目的本回顾性研究旨在评估洛杉矶新奥尔良市一家三级医疗中心的产妇和先天性梅毒（CS）管理趋势：研究设计：使用ICD-9/10编码确定洛杉矶新奥尔良市图罗医院五年内所有产妇和新生儿梅毒病例。对病历中的人口统计学和产科变量、梅毒诊断阶段、化验值和治疗方案进行审查。记录了新生儿的治疗情况和其他结果：研究期间共发现 106 对受感染的母婴。其中 73 份病历可供查阅。41%的妇女（n = 30）根据其疾病阶段接受了不适当的治疗。9%的新生儿（6 例）被发现有 CS 症状，但其中只有 83.3% 的新生儿被送入新生儿重症监护室。如果母亲没有得到充分治疗，只有 20% 的婴儿（6 人）得到了青霉素延长疗法的充分治疗。此外，只有 63.0% 的新生儿进行了非青霉素滴度检测：随着CS发病率的上升，必须严格遵守2015年美国疾病预防控制中心梅毒治疗指南。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Infectious Diseases in Obstetrics and Gynecology Medicine-Obstetrics and Gynecology

CiteScore

3.80

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Infectious Diseases in Obstetrics and Gynecology aims to disseminate new and important information to clinicians and other health care providers, scientists, and researchers involved in the study or treatment of infectious diseases, especially those affecting the female patient. Its ultimate aim is to advance knowledge and encourage research, thereby improving the prevention or diagnosis and treatment of patients affected by such diseases.