The Promise of Pragmatic Clinical Trials Embedded in Learning Health Systems.

Leah Tuzzio, Eric B Larson
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引用次数: 0

Abstract

This commentary describes the need for a different context to clinical research that could speed the discovery and implementation of evidence-based advancements to health care delivery. Pragmatic clinical trials (PCTs) are a promising type of trial conducted within real-world health care delivery systems like organizations within the Health Care Systems Research Network, that embrace research as part of their culture of continuous learning and improvement. In these learning health systems (LHSs) clinical practice influences research and vice versa. A goal of LHSs is to operationalize evidence generated by research, particularly PCTs, into improvements that are sustained after a trial ends. PCTs that demonstrate value to health systems and foster implementation could reduce delays in translating research into practice.

在学习健康系统中嵌入实用临床试验的前景。
这篇评论描述了临床研究需要一个不同的背景,以加快发现和实施循证医疗保健进展。实用临床试验(PCT)是在现实世界的医疗保健提供系统中进行的一种很有前途的试验,如医疗保健系统研究网络中的组织,这些组织将研究作为其持续学习和改进文化的一部分。在这些学习健康系统中,临床实践影响研究,反之亦然。LHS的一个目标是将研究产生的证据,特别是PCT,转化为试验结束后持续的改进。证明对卫生系统有价值并促进实施的PCT可以减少将研究转化为实践的延误。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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