A Case of Eosinophilic Granulomatosis with Polyangiitis Complicated with A IgG4 Related Disease Like Symptoms.

Pub Date : 2018-11-04 eCollection Date: 2018-01-01 DOI:10.1155/2018/3763084
Suguru Sato, Julia Morimoto, Yasuharu Oguchi, Takashi Umeda, Takaya Kawamata, Mami Rikimaru, Tatsuhiko Koizumi, Ryuichi Togawa, Yasuhito Suzuki, Yuki Sato, Manabu Uematsu, Hiroyuki Minemura, Takefumi Nikaido, Atsuro Fukuhara, Junpei Saito, Kenya Kanazawa, Yoshinori Tanino, Mitsuru Munakata, Yoko Shibata
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引用次数: 4

Abstract

We report a case of eosinophilic granulomatosis with polyangiitis (EGPA) complicated with a IgG4 related disease like symptoms presenting as eyelid swellings. In the present case, the serum level of IgG4 and the ratio of IgG4 to IgG were generally increased by the disease course of EGPA. Considering the course of clinical symptoms, there is a possibility that orbital manifestations were one of the clinical features during the disease course of EGPA while the histological features of right eyelid tissue and other ocular manifestations were consistent with the diagnosis of IgG4 related disease.

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嗜酸性肉芽肿病合并多血管炎合并IgG4相关疾病样症状1例。
我们报告一例嗜酸性肉芽肿病合并多血管炎(EGPA)并发IgG4相关疾病,症状表现为眼睑肿胀。本病例血清IgG4水平及IgG4 / IgG比值普遍随EGPA病程的增加而升高。结合临床症状的过程,有可能眼窝表现是EGPA病程中的临床特征之一,而右眼眼睑组织的组织学特征及其他眼部表现与IgG4相关疾病的诊断一致。
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