Oral focal mucinosis in adolesence: a sparingly diagnosed clinicopathologic entity.

Q3 Pharmacology, Toxicology and Pharmaceutics
Samreen Taufiq, Madhusudan Astekar, Sowmya Gv, Manjunatha Bs, Shipra Saxena
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Abstract

Objective: Oral focal mucinosis an oral counterpart of cutaneous focal mucinosis, is a rare disease of unknown etiology. Its pathogenesis may be due to the overproduction of hyaluronic acid by a fibroblast, at the expense of collagen production, resulting in focal myxoid degeneration of the connective tissue, primarily affecting the mucosa overlying the bone. Oral focal mucinosis occurs predonderantly in adults during the fourth and fifth decade of life, although it has been reported sparingly in children and adolescents. It has no distinctive clinical features, as the diagnosis is solely based on the histopathological features and treatment involves complete surgical excision. Recurrence is unreported. This case report put forward the clinical and histological presentation and consequent management of Oral focal mucinosis in an adolescent female patient.

青少年口腔局灶性黏液病:一种极少被诊断的临床病理实体。
目的:口腔局灶性黏液病是一种病因不明的罕见疾病,与皮肤局灶性黏液病相对应。其发病机制可能是由于成纤维细胞产生过多的透明质酸,以牺牲胶原蛋白的产生为代价,导致结缔组织的局灶性粘液样变性,主要影响骨上覆盖的粘膜。口腔局灶性黏液病主要发生在40岁和50岁的成年人中,尽管在儿童和青少年中也有少量报道。它没有明显的临床特征,因为诊断完全基于组织病理学特征,治疗涉及完全手术切除。复发未见报道。本病例报告提出了一名青少年女性口腔局灶性黏液病的临床和组织学表现及相应的治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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