{"title":"bevacizumab (Avastin°) in persistent, recurrent or metastatic cervical cancer: Prolongs survival by a few months, but highly toxic.","authors":"","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In an unblinded trial in 452 patients with persistent, recurrent or metastatic cervical cancer, adding bevacizumab to other cytotoxic drugs prolonged median survival by 4 months, but adverse effects were often severe and sometimes fatal. Tailored symptomatic care is also a valid option.</p>","PeriodicalId":35983,"journal":{"name":"Prescrire International","volume":"25 175","pages":"233"},"PeriodicalIF":0.0000,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Prescrire International","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
In an unblinded trial in 452 patients with persistent, recurrent or metastatic cervical cancer, adding bevacizumab to other cytotoxic drugs prolonged median survival by 4 months, but adverse effects were often severe and sometimes fatal. Tailored symptomatic care is also a valid option.