Quadriceps Impairment Is Associated with Gait Mechanics in Young Adults with Obesity.

IF 5.4 3区材料科学 Q2 CHEMISTRY, PHYSICAL

ACS Applied Energy Materials Pub Date : 2019-05-01 DOI:10.1249/MSS.0000000000001891

Michael N Vakula, Koren L Fisher, Steven A Garcia, Skylar C Holmes, Brett K Post, Pablo B Costa, Derek N Pamukoff

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引用次数: 21

Abstract

Purpose: Obesity influences gait and muscle function, which may contribute to knee osteoarthritis. This study aimed 1) to compare gait biomechanics and quadriceps function between individuals with and without obesity and 2) to examine the association between quadriceps function and gait biomechanics.

Methods: Forty-eight individuals with and 48 without obesity participated and were matched on age and sex. Gait biomechanics at standardized and self-selected speeds were used to assess peak vertical ground reaction force (vGRF), vertical loading rate (vLR), internal knee extension moment (KEM), peak knee flexion angle (KFA), knee flexion excursion (KFE), and knee joint stiffness. Quadriceps function was assessed using peak isometric strength (peak torque), early (RTD100) and late (RTD200) rate of torque development (RTD), and vastus lateralis cross-sectional area (CSA) and echo intensity (EI).

Results: When normalized to fat-free mass, individuals with obesity had lower RTD100 (P = 0.04) and RTD200 (P = 0.02) but higher vastus lateralis CSA (P < 0.01) and EI (P < 0.01) compared with normal weight controls. The group-speed interaction was significant for normalized vGRF (P < 0.01), normalized vLR (P = 0.02), normalized KEM (P = 0.03), and normalized knee joint stiffness (P = 0.02). Post hoc analyses indicate a smaller normalized vGRF and normalized KEM, and lower knee joint stiffness in individuals with obesity compared with normal weight controls at self-selected speed. There were main effects of speed for all kinematic and kinetic variables, and body mass index group for all absolute kinetic variables as well as normalized vGRF (all P < 0.001). A lower vastus lateralis EI (P = 0.04) and greater RTD100 (P < 0.01) were associated with a larger KEM in individuals with obesity.

Conclusion: Individuals with obesity have quadriceps dysfunction that is weakly associated with KEM during walking. Exercise interventions that improve quadriceps function may improve walking mechanics.

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四头肌损伤与肥胖青年的步态力学有关。

目的:肥胖影响步态和肌肉功能，可能导致膝骨关节炎。本研究旨在1)比较肥胖和非肥胖个体的步态生物力学和股四头肌功能;2)研究股四头肌功能和步态生物力学之间的关系。方法:48名肥胖个体和48名非肥胖个体参与研究，年龄和性别匹配。采用标准化和自选速度下的步态生物力学来评估峰值垂直地面反作用力(vGRF)、垂直加载率(vLR)、膝关节内伸力矩(KEM)、峰值膝关节屈曲角(KFA)、膝关节屈曲偏移(KFE)和膝关节刚度。采用峰值等距强度(峰值扭矩)、早期(RTD100)和晚期(RTD200)扭矩发展速率(RTD)、股外侧横截面积(CSA)和回声强度(EI)评估股四头肌功能。结果:与正常体重对照者相比，肥胖组RTD100 (P = 0.04)和RTD200 (P = 0.02)较低，股外侧肌CSA (P < 0.01)和EI (P < 0.01)较高。组速交互作用对归一化vGRF (P < 0.01)、归一化vLR (P = 0.02)、归一化KEM (P = 0.03)和归一化膝关节刚度(P = 0.02)均有显著影响。事后分析表明，在自我选择的速度下，与正常体重对照者相比，肥胖个体的标准化vGRF和标准化KEM更小，膝关节刚度更低。速度组对所有运动学和动力学变量有主要影响，体重指数组对所有绝对动力学变量和归一化vGRF有主要影响(均P < 0.001)。在肥胖个体中，较低的股外侧肌EI (P = 0.04)和较大的RTD100 (P < 0.01)与较大的KEM相关。结论:肥胖个体有股四头肌功能障碍，与步行时KEM有弱相关性。改善股四头肌功能的运动干预可以改善步行力学。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Energy Materials Materials Science-Materials Chemistry

CiteScore

10.30

自引率

6.20%

发文量

1368

期刊介绍： ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.