Prevalence of oral squamous cell carcinoma in Bareilly Region: A seven year institutional study.

Q3 Pharmacology, Toxicology and Pharmaceutics
Madhusudan Astekar, Samreen Taufiq, Gaurav Sapra, Ashutosh Agarwal, Aditi Murari, Harshita Putthia
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Abstract

Background: Oral squamous cell carcinoma is a major contributor to disability and death caused by malignant tumors. Variations in social, cultural, and geographic factors affect the tumor behavior and response to treatment. In this study, we undertake a seven years institutional review and analysis of Oral squamous cell carcinoma cases in Bareilly.

Materials and methods: A total of 1938 histologically diagnosed cases during the period of seven years i.e. from 2010 to 2016 were extracted from the archives of Department of Oral & Maxillofacial Pathology, Institute of Dental Sciences, Bareilly and evaluated to know the prevalence of Oral squamous cell carcinoma. The details like age, sex, habits and anatomical site were also recorded from the archived patient's case sheets.

Results: Out of the total 1938 cases, 318 were found to be Oral squamous cell carcinoma of which 232 were males and 86 were females. Incidence was highest in 40-49 year age group. The most common site was buccal mucosa (190 cases), followed by tongue (68 cases). Most lesions were well differentiated Oral squamous cell carcinoma (230 cases). Patients with poorly differentiated lesions had a comparatively lower mean age than their counterparts with other histological varieties.

Conclusion: The pattern of Oral squamous cell carcinoma differs from that of previous studies in relation to incidence and age correlation with the grade of carcinoma. The majority of the lesions were well differentiated. There is a need for intensive oral health awareness to encourage early presentation to cancer center as early detection will further enhance prognosis.

巴雷利地区口腔鳞状细胞癌患病率:一项为期七年的机构研究。
背景:口腔鳞状细胞癌是恶性肿瘤致残和死亡的主要原因。不同的社会、文化和地理因素会影响肿瘤的行为和对治疗的反应。在这项研究中,我们进行了7年的机构回顾和分析口腔鳞状细胞癌病例在巴雷利。材料与方法:选取巴雷利口腔科学研究所口腔颌面病理科档案中2010 - 2016年7年间组织学诊断病例1938例,进行评估,了解口腔鳞状细胞癌的患病率。年龄、性别、习惯和解剖部位等细节也从存档的患者病例表中记录下来。结果:1938例口腔鳞癌318例,其中男性232例,女性86例。发病率以40 ~ 49岁年龄组最高。最常见部位为颊黏膜(190例),其次为舌部(68例)。病变多为高分化口腔鳞状细胞癌(230例)。低分化病变患者的平均年龄相对低于其他组织学类型的患者。结论:口腔鳞状细胞癌的类型与以往的研究不同,发病率和年龄与癌的分级相关。多数病变分化良好。有必要加强口腔健康意识,鼓励早期到癌症中心就诊,因为早期发现将进一步提高预后。
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