Srcasm Regulates Tyrosine Kinases in Skin Cancer: Implications for Precision Medicine

Q2 Medicine

Journal of Investigative Dermatology Symposium Proceedings Pub Date : 2018-12-01 DOI:10.1016/j.jisp.2018.10.006

Vivian Lee , Xiaoping Yang , Stephen Prouty , Tzvete Denchev , Christine Marshall , Hiroshi Maeno , Hasan Bashir , Conor O’Day , John T. Seykora

引用次数: 0

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Srcasm在皮肤癌中调节酪氨酸激酶:对精准医学的影响

皮肤鳞状细胞癌(cSCC)是人类第二大常见癌症，在美国每年的发病率约为70万例(Rogers et al.， 2010)。众所周知，cSCC与阳光照射密切相关，特别是UVB和UVA，以及其他危险因素，如人乳头瘤病毒感染、免疫缺陷和特定药物(Ratushny et al.， 2012)。然而，导致肿瘤发展的生物学事件的确切顺序仍然未知。由于预计未来cSCCs患者的发病率会更高，因此迫切需要阐明调节cSCCs形成的分子途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Investigative Dermatology Symposium Proceedings 医学-皮肤病学

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期刊介绍： Journal of Investigative Dermatology Symposium Proceedings (JIDSP) publishes peer-reviewed, invited papers relevant to all aspects of cutaneous biology and skin disease. Papers in the JIDSP are often initially presented at a scientific meeting. Potential topics include biochemistry, biophysics, carcinogenesis, cellular growth and regulation, clinical research, development, epidemiology and other population-based research, extracellular matrix, genetics, immunology, melanocyte biology, microbiology, molecular and cell biology, pathology, pharmacology and percutaneous absorption, photobiology, physiology, and skin structure.