The 6-m timed hop test is a prognostic factor for outcomes in patients with meniscal tears treated with exercise therapy or arthroscopic partial meniscectomy: a secondary, exploratory analysis of the Odense-Oslo meniscectomy versus exercise (OMEX) trial.

Nina Jullum Kise, Ewa M Roos, Silje Stensrud, Lars Engebretsen, May Arna Risberg
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引用次数: 7

Abstract

Purpose: To identify the prognostic factors for 2-year patient-reported outcomes in middle-aged patients with degenerative meniscal tears treated with exercise therapy (ET) or arthroscopic partial meniscectomy (APM).

Methods: One hundred and seven patients, with mean age 49.6 (SD 6.2) years and BMI 25.7 (SD 3.7), were included in this analysis of data from the OMEX trial ( http://www.clinicaltrials.gov NCT01002794). Linear and Poisson regression models were built to explore the associations between potential prognostic factors (patient characteristics, knee function-related and disease-related factors) and 2-year patient-reported outcomes: the Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales Pain, Symptoms, ADL, Sport/Rec, QoL and 5-point Global Rating of Change scales for knee pain (GRC Pain) and function (GRC Function). Analyses were performed for the whole cohort and for the two treatment groups (n = 55 and 52) with adjustments for age, sex, BMI and baseline KOOS.

Results: For the whole cohort, a 1-s better baseline 6-m timed hop test result was associated with 3.1-7.1 points better 2-year scores for all KOOS subscales (95% CIs 1.1-5.2 to 4.1-10.1 points). A 1.61-2.80 s better test was associated with scores equivalent to previously calculated clinical relevant differences for each KOOS subscale. For the groups of patients treated with ET and APM, respectively, 2.09-3.60 s and 0.63-1.99 s better tests were associated with clinical relevant differences. For the whole cohort, a 1-s better test was associated with 26% (95% CI 15-38%) and 22% (95% CI 11-34%) higher possibility for better or much better GRC Pain and Function scores. Patients treated with ET had 17% (95% CI 2-33%) increased possibility for better or much better GRC Pain score, and patients treated with APM had 65% (95% CI 32-108%) and 70% (95% CI 38-109%) increased possibility for better or much better GRC Pain and Function scores.

Conclusions: The 6-m timed hop test result was a significant prognostic factor for 2-year patient-reported outcomes in middle-aged patients with degenerative meniscal tears, especially in those treated with APM.

Level of evidence: II.

6米计时跳跃试验是运动疗法或关节镜半月板部分切除术治疗半月板撕裂患者预后的一个预测因素:对Odense-Oslo半月板切除术与运动(OMEX)试验的二次探索性分析。
目的:探讨运动疗法(ET)或关节镜半月板部分切除术(APM)治疗的中年退行性半月板撕裂患者2年预后的影响因素。方法:纳入117例患者,平均年龄49.6 (SD 6.2)岁,BMI 25.7 (SD 3.7),数据来自OMEX试验(http://www.clinicaltrials.gov NCT01002794)。建立线性和泊松回归模型来探讨潜在预后因素(患者特征、膝关节功能相关和疾病相关因素)与患者报告的2年预后之间的关系:膝关节损伤和骨关节炎结局评分(oos)亚量表疼痛、症状、ADL、运动/Rec、QoL和膝关节疼痛(GRC Pain)和功能(GRC function)的5分全球变化评分量表。对整个队列和两个治疗组(n = 55和52)进行分析,并对年龄、性别、BMI和基线KOOS进行调整。结果:在整个队列中,基线6米计时跳测试结果提高1秒与所有oos子量表的2年得分提高3.1-7.1分相关(95% ci 1.1-5.2至4.1-10.1分)。1.61-2.80 s更好的测试与先前计算的每个kos分量表的临床相关差异相关。对于分别接受ET和APM治疗的患者组,2.09-3.60 s和0.63-1.99 s的较好测试与临床相关差异相关。对于整个队列,1-s更好的测试与26% (95% CI 15-38%)和22% (95% CI 11-34%)更高或更佳的GRC疼痛和功能评分的可能性相关。接受ET治疗的患者获得更好或更佳GRC疼痛评分的可能性增加17% (95% CI 2-33%),而接受APM治疗的患者获得更好或更佳GRC疼痛和功能评分的可能性增加65% (95% CI 32-108%)和70% (95% CI 38-109%)。结论:6米定时跳试验结果是中年退行性半月板撕裂患者2年预后的重要因素,特别是那些接受APM治疗的患者。证据水平:II。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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