PERFORMANCE OF TOTAL PANCREATECTOMY FOR PANCREATIC MALIGNANCIES.

Klinichna khirurgiia Pub Date : 2016-10-01
A I Dronov, S V Zemskov, E A Kryuchina
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引用次数: 0

Abstract

Lethality, morbidity, survival indices and metabolic consequences of total pancreatec' tomy (TP), performed in patients, suffering pancreatic tumors, were analyzed. There were retrospectively analyzed 35 TP оperations, including 5— urgent, 30 — elective, performed in a single center. General lethality have constituted 20% (7 patients died), and after elective ТP — 6.7% (2 died). Complications rate after elective TP have consti' tuted 40%; survival mediana—18 mo; indices of a 3—year survival — 40%, and a 5— year one — 13.3%. Most frequently revealed metabolic changes after ТP — pancreatic exocrine insufficiency, pancreatogenic diabetes, changes in a lipid metabolism in hepatocytes. Our experience witnesses expediency of ТP introduction into surgical practice in specialized centers of Ukraine with results, which are matching a worldwide.

全胰腺切除术治疗胰腺恶性肿瘤的效果。
分析胰腺肿瘤患者行全胰切除术(TP)的致死率、发病率、生存指标和代谢后果。回顾性分析35例TP手术,其中急诊5例,择期30例。一般死亡率为20%(7例死亡),择期后死亡率为ТP - 6.7%(2例死亡)。选择性TP术后并发症占40%;生存期:18个月;3年生存率为40%,5年生存率为13.3%。最常见的代谢变化发生在ТP -胰分泌功能不全,胰源性糖尿病,肝细胞脂质代谢的变化。我们的经验见证了ТP在乌克兰专业中心引入外科实践的方便性,其结果与世界范围内的结果相匹配。
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