Lifetime Alcohol Use Patterns and Risk of Diabetes Onset in the National Alcohol Survey.

IF 3.2 3区 医学 Q1 Medicine
Alcoholism, clinical and experimental research Pub Date : 2019-02-01 Epub Date: 2018-12-10 DOI:10.1111/acer.13924
William C Kerr, Yu Ye, Edwina Williams, Camillia K Lui, Thomas K Greenfield, E Anne Lown
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引用次数: 13

Abstract

Background: Studies of the role of alcohol use in diabetes risk have rarely included lifetime alcohol use measures, including the frequency of heavy occasions, or evaluated risks among Black or Hispanic respondents in US samples.

Methods: Data from the 2014 to 2015 National Alcohol Survey of the U.S. population were used to estimate diabetes risk from drinking patterns at the time of onset in Cox proportional hazards models in a retrospective cohort design. Models for the population, males and females, and for White, Black, and Hispanic respondents of both genders were estimated using 2 versions of drinking pattern groupings at each age.

Results: While a number of significant results were found with the first version of the drinking measures, we focus on those confirmed with measures from responses strictly prior to the age of risk estimation. Compared to the lifetime abstainer group, the "drinking at least weekly with less than monthly 5+" group had a significantly lower hazard ratio (HR) for the total sample (HR = 0.64) and among Whites (HR = 0.42). Significantly reduced risks were found in the same models for those who drank 5+ at least monthly but not weekly. No significantly elevated risks were found for either current or prior heavy occasion drinking.

Conclusions: These results are consistent with some prior studies in finding reduced risks for regular light-to-moderate drinkers, but not consistent with findings from other studies showing increased risk from heavy occasion drinking, particularly among women. New and larger studies with well-defined drinking pattern measures are needed, particularly for U.S. Blacks and Hispanics, to address varying results in this literature.

国家酒精调查中终生酒精使用模式和糖尿病发病风险
背景:关于酒精使用在糖尿病风险中的作用的研究很少包括终生酒精使用措施,包括重度饮酒的频率,或评估美国样本中黑人或西班牙裔受访者的风险。方法:采用回顾性队列设计的Cox比例风险模型,利用2014 - 2015年美国人口全国酒精调查数据,估计发病时饮酒模式对糖尿病的风险。人口模型,男性和女性,以及白人、黑人和西班牙裔两种性别的受访者在每个年龄段使用两种版本的饮酒模式分组进行估计。结果:虽然在第一版饮酒测量中发现了一些重要的结果,但我们关注的是那些严格早于风险估计年龄的反应所证实的结果。与终生戒酒组相比,“至少每周饮酒少于每月饮酒5+”组的总样本(HR = 0.64)和白人(HR = 0.42)的风险比(HR)显著降低。在相同的模型中,那些每月至少喝5杯以上而不是每周喝5杯以上的人的风险明显降低。目前或之前的大量场合饮酒均未发现显著升高的风险。结论:这些结果与之前的一些研究结果一致,这些研究发现定期轻度至中度饮酒者的风险降低,但与其他研究结果不一致,这些研究发现大量饮酒会增加风险,特别是在女性中。需要新的和更大规模的研究,明确的饮酒模式测量,特别是针对美国黑人和西班牙裔,以解决文献中不同的结果。
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来源期刊
CiteScore
5.90
自引率
9.40%
发文量
219
审稿时长
1 months
期刊介绍: Alcoholism: Clinical and Experimental Research''s scope spans animal and human clinical research, epidemiological, experimental, policy, and historical research relating to any aspect of alcohol abuse, dependence, or alcoholism. This journal uses a multi-disciplinary approach in its scope of alcoholism, its causes, clinical and animal effect, consequences, patterns, treatments and recovery, predictors and prevention.
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