Brain mechanisms controlling Pavlovian fear conditioning.

IF 1.3 4区 心理学
Joanna O Y Yau, Gavan P McNally
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引用次数: 19

Abstract

A key insight of associative learning theory is that learning depends on the actions of prediction error: a discrepancy between the actual and expected outcomes of a conditioning trial. This view of learning has inspired, and in turn been supported by, work in the neurosciences ranging from single unit recording and neuroimaging studies to pharmacological, chemogenetic, and optogenetic interventions. Here we review evidence describing how error-correcting learning rules are instantiated in the activity of distributed neural circuits controlling the effectiveness of unconditioned stimuli during Pavlovian fear conditioning. We show that these prediction error signals, controlling variations in event processing, are fundamental to Pavlovian fear association formation. We also argue that variations in event processing are embedded within multiplexed learning signals and that a coherent understanding of the nature and relationships between these multiple signals at specific times during the conditioning trial is needed. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

控制巴甫洛夫恐惧条件反射的大脑机制。
联想学习理论的一个关键观点是,学习依赖于预测误差的行为:条件反射试验的实际结果与预期结果之间的差异。这种学习的观点启发了神经科学领域的工作,从单单元记录和神经成像研究到药理学、化学发生和光遗传干预,反过来又得到了这些工作的支持。在此,我们回顾了描述在巴甫洛夫恐惧条件反射过程中控制非条件刺激有效性的分布式神经回路活动中如何实例化纠错学习规则的证据。我们发现这些预测误差信号,控制事件处理的变化,是巴甫洛夫恐惧联想形成的基础。我们还认为,事件处理的变化嵌入在多路学习信号中,需要在条件反射试验的特定时间对这些多路信号的性质和关系有一个连贯的理解。(PsycINFO数据库记录(c) 2018 APA,版权所有)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
自引率
23.10%
发文量
0
审稿时长
>12 weeks
期刊介绍: The Journal of Experimental Psychology: Animal Learning and Cognition publishes experimental and theoretical studies concerning all aspects of animal behavior processes.
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