{"title":"Sparse concordance-assisted learning for optimal treatment decision.","authors":"Shuhan Liang, Wenbin Lu, Rui Song, Lan Wang","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>To find optimal decision rule, Fan et al. (2016) proposed an innovative concordance-assisted learning algorithm which is based on maximum rank correlation estimator. It makes better use of the available information through pairwise comparison. However the objective function is discontinuous and computationally hard to optimize. In this paper, we consider a convex surrogate loss function to solve this problem. In addition, our algorithm ensures sparsity of decision rule and renders easy interpretation. We derive the <i>L</i> <sub>2</sub> error bound of the estimated coefficients under ultra-high dimension. Simulation results of various settings and application to STAR*D both illustrate that the proposed method can still estimate optimal treatment regime successfully when the number of covariates is large.</p>","PeriodicalId":50161,"journal":{"name":"Journal of Machine Learning Research","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226264/pdf/nihms-987205.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Machine Learning Research","FirstCategoryId":"94","ListUrlMain":"","RegionNum":3,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"AUTOMATION & CONTROL SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
To find optimal decision rule, Fan et al. (2016) proposed an innovative concordance-assisted learning algorithm which is based on maximum rank correlation estimator. It makes better use of the available information through pairwise comparison. However the objective function is discontinuous and computationally hard to optimize. In this paper, we consider a convex surrogate loss function to solve this problem. In addition, our algorithm ensures sparsity of decision rule and renders easy interpretation. We derive the L2 error bound of the estimated coefficients under ultra-high dimension. Simulation results of various settings and application to STAR*D both illustrate that the proposed method can still estimate optimal treatment regime successfully when the number of covariates is large.
期刊介绍:
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