Exploratory study of the reproducibility of the SCore for INtrinsic and EXtrinsic skin aging (SCINEXA) scale in "Ruta Escondida de la Mitad del Mundo", Ecuador, 2017.

Q2 Medicine

BMC Dermatology Pub Date : 2018-11-06 DOI:10.1186/s12895-018-0078-9

Martha Fors, Santiago Palacios, Kirsten Falcon, Karla Ventimilla, Lilia Simbaña, Carlos Lagos, Nélida Lasso, Carlos Navas

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引用次数: 1

Abstract

Background: Few studies have been published related to the analysis of different skin aging parameters for whole-body skin using the SCINEXA scale for skin damage. The aim of this study was to evaluate the reproducibility of the SCINEXA scale (SCore for INtrinsic and EXtrinsic skin Aging) in South-Americans non-Caucasian population of a region of Ecuador.

Methods: Exploratory observational study. Thirty subjects of both genders, over 40 years old and living in a rural area with particular characteristics regarding sun exposure were included. The SCINEXA scale was applied at three different time points to assess its reproducibility. Repeated measures analysis of variance was used for comparison of mean SCINEXA scores. Intraclass correlation coefficient, 95% CI and "Cronbach's alpha" coefficient were performed to measure reproducibility.

Results: Among participants, 86.7% were female; mean age was over 67 years old, with mainly low educational level, and almost half had more than six hours of sun exposure per day. Test-retest reproducibility of this scale demonstrated almost perfect agreement. The SCINEXA score was greater than 2 points in half of the subjects, reflecting aging due to sun exposure.

Limitations: Most participants were women from one town in a particular geographical area, and the sample size was small. Genetic determinants of skin phenotypes were not assessed.

Conclusions: The SCINEXA score is reproducible in South American non-Caucasian subjects of a particular region of the country. Damage from sun exposure was evident in participants.

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2017年厄瓜多尔《世界报》对内在和外在皮肤老化评分(sciexa)量表再现性的探索性研究。

背景:使用sciexa皮肤损伤量表分析全身皮肤不同老化参数的相关研究很少发表。本研究的目的是评估sciexa量表(内在和外在皮肤老化评分)在厄瓜多尔地区南美非高加索人群中的可重复性。方法:探索性观察研究。研究对象包括30名男女，年龄在40岁以上，居住在农村地区，在阳光照射方面有特殊特点。在三个不同的时间点应用sciexa量表来评估其再现性。sciexa平均分比较采用重复测量方差分析。用类内相关系数、95% CI和“Cronbach’s alpha”系数来衡量再现性。结果:参与者中女性占86.7%;平均年龄在67岁以上，主要受教育程度较低，几乎一半的人每天日照时间超过6小时。该量表的复测再现性证明了几乎完美的一致性。半数受试者的sciexa得分超过2分，反映了日晒导致的衰老。局限性:大多数参与者是来自特定地理区域的一个城镇的妇女，样本量很小。未评估皮肤表型的遗传决定因素。结论:sciexa评分在该国特定地区的南美非白种人受试者中是可重复的。暴露在阳光下的损伤在参与者身上很明显。

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BMC Dermatology Medicine-Dermatology

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期刊介绍： BMC Dermatology is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of skin disorders, as well as related molecular genetics, pathophysiology, and epidemiology. BMC Dermatology (ISSN 1471-5945) is indexed/tracked/covered by PubMed, MEDLINE, CAS, EMBASE, Scopus and Google Scholar.