Hyperbaric Oxygen Therapy in Ischaemic Foot Ulcers in Type 2 Diabetes: A Clinical Trial.

The Open Cardiovascular Medicine Journal Pub Date : 2018-08-31 eCollection Date: 2018-01-01 DOI:10.2174/1874192401812010080

Sarah Perren, Alfred Gatt, Nikolaos Papanas, Cynthia Formosa

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引用次数: 18

Abstract

Background and aims: Several treatment modalities and protocols for ischaemic foot ulcers are available. However, little consensus exists on optimal treatment. The aim of this study was to compare Standard Wound Care (SWC) alone vs. SWC with adjunct hyperbaric oxygen therapy (HBOT) in the treatment of ischaemic Diabetic Foot Ulcers (DFUs).

Patients and methods: Twenty-six patients with Type 2 Diabetes Mellitus (T2DM) presenting with a newly diagnosed ischaemic foot ulcer were included. These were divided into group A (SWC with adjunct HBOT) and group B (SWC only). Participants were followed every week for 4 weeks and their ulcers were measured for their surface area and depth to assess any change in wound size.

Results: Both treatment arms succeeded in reducing ulcer area and depth (p<0.001). However, ulcer area (p<0.001) and depth (p<0.001) exhibited superior improvement in group A.

Conclusion: Adjunctive HBOT appears to improve wound healing in ischaemic DFUs and merits further study.

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高压氧治疗2型糖尿病缺血性足溃疡的临床试验

背景和目的:缺血性足溃疡的几种治疗方式和方案是可用的。然而，对于最佳治疗方法却鲜有共识。本研究的目的是比较标准伤口护理(SWC)单独与SWC辅助高压氧治疗(HBOT)在缺血性糖尿病足溃疡(DFUs)治疗中的作用。患者和方法:纳入26例新诊断为缺血性足部溃疡的2型糖尿病(T2DM)患者。这些患者被分为A组(SWC合并HBOT)和B组(仅SWC)。参与者每周随访4周，测量溃疡的表面积和深度，以评估伤口大小的任何变化。结果:两个治疗组均成功地减少了溃疡面积和深度(p结论:辅助HBOT可改善缺血性dfu的伤口愈合，值得进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Open Cardiovascular Medicine Journal

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