[Chemical Constituents of Alkaloids from the Bark of Sophora japonica].

中药材 Pub Date : 2016-09-01

Long Pan, Man Zhang, He-ru Chen

引用次数: 0

Abstract

Objective: To study the chemical constituents in the bark of Sophora japonica.

Methods: The chemical constituents were separated and purified by silica gel,Sephadex LH-20 column chromatography,and HPLC. Their structures were identified by various spectroscopic analyses.

Results: Eleven compounds were obtained from the bark of Sophora japonica. Their structures were identified as( +)-oxymatrine( 1),isosophoridine( 2),lupanine( 3),( +)-matrine( 4),( +)-sophoramine( 5),(-)-14β-hydroxymatrine( 6),(-)-7,11-dehydromatrine( 7),alopecurin A( 8),( +)-sophoranol( 9),α-isolupanine( 10) and( +)-allomatrine( 11).

Conclusion: Compounds 2,3,5 and 7 ~ 11 are isolated from this plant for the first time.

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[苦参树皮生物碱的化学成分]。

目的:研究苦参树皮的化学成分。方法:采用硅胶柱层析、Sephadex LH-20柱层析和高效液相色谱法对其化学成分进行分离纯化。通过各种光谱分析鉴定了它们的结构。结果:从苦参树皮中分离得到11个化合物。它们的结构分别为(+)-氧化苦参碱(1)、异苦参碱(2)、lupanine(3)、(+)-苦参碱(4)、(+)-苦参胺(5)、(-)-14β-羟基苦参碱(6)、(-)-7,11-脱氢苦参碱(7)、alopecurin A(8)、(+)-苦参醇(9)、α-异黄酮氨酸(10)和(+)-异苦参碱(11)。结论:化合物2、3、5和7 ~ 11均为首次从该植物中分离得到。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

中药材

自引率

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11364

期刊介绍： "Chinese Materia Medica" magazine was founded in 1978. It is a national-level academic journal of Chinese medicine science and technology approved by the State Science and Technology Commission and the Press and Publication Administration for public distribution at home and abroad. It is sponsored by the Chinese Materia Medica Information Center of the State Food and Drug Administration and is publicly distributed at home and abroad. It mainly reports on new technologies, new methods and new achievements in the production, scientific research and business management of Chinese medicine, and serves to promote the production and scientific and technological development of Chinese medicine, improve the output and quality of Chinese medicine, improve business management, and prosper the Chinese medicine industry.