White matter changes in patients with mild traumatic brain injury: MRI perspective.

Q3 Medicine
Concussion Pub Date : 2017-03-22 eCollection Date: 2017-06-01 DOI:10.2217/cnc-2016-0028
Ponnada A Narayana
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引用次数: 67

Abstract

This review focuses on white matter (WM) changes in mild traumatic brain injury (mTBI) as assessed by multimodal MRI. All the peer reviewed publications on WM changes in mTBI from January 2011 through September 2016 are included in this review. This review is organized as follows: introduction to mTBI, the basics of multimodal MRI techniques that are potentially useful for probing the WM integrity, summary and critical evaluation of the published literature on the application of multimodal MRI techniques to assess the changes of WM in mTBI, and correlation of MRI measures with behavioral deficits. The MRI-pathology correlation studies based on preclinical models of mTBI are also reviewed. Finally, the author's perspective of future research directions is described.

轻度外伤性脑损伤患者脑白质改变:MRI透视。
本文综述了多模态MRI评估的轻度创伤性脑损伤(mTBI)中白质(WM)的变化。从2011年1月到2016年9月,所有关于mTBI中WM变化的同行评议出版物都被纳入本综述。这篇综述的组织如下:mTBI的介绍,多模态MRI技术的基础知识,这些技术可能有助于探测WM的完整性,总结和批判性地评估多模态MRI技术在mTBI中应用于评估WM变化的已发表文献,以及MRI测量与行为缺陷的相关性。本文还综述了基于mTBI临床前模型的mri病理相关性研究。最后,阐述了作者对未来研究方向的展望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Concussion
Concussion Medicine-Neurology (clinical)
CiteScore
2.70
自引率
0.00%
发文量
2
审稿时长
12 weeks
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