[DYNAMICS DAILY VARIABILITY OF HEART RATE AND BLOOD PRESSURE IN CHRONIC HEART FAILURE].

Abstract

Analysis of results the telemetry monitoring of daily dynamics of heart rate variability in the control and experimental rats with chronic heart failure (CHF) has revealed different mechanisms of vegetative regulation of heart rate. In animals with chronic heart failure found a significant worsening of cardiac dysfunction at night and in the morning, accompanied by an increase in the variability of systolic and pulse pressure as well as the number of QTc intervals longer than 220 ms and Tpeak-Tend. This indicates the maximal high risk of fatal ventricular arrhythmias, leading to sudden cardiac death.