[COMPARATIVE CHARACTERIZATION OF HYALURONIDASE ISOFORMS OF THE 1ST TYPE IN SOMATIC TISSUES AND SERUM OF WHITE RATS].

S G Dzgoev
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Abstract

There are identified 3 proteins with molecular mass of 63, 73 and 132 kDa, exhibiting the properties of the hyaluronidase of the 1st type in the liver, spleen, renal papilla, skin and serum by the method of zymography. A protein with a molecular mass of 73 kDa was detected in all studied tissues and serum, while protein with a molecular mass of 63 kDa was present only in the tissues, and the protein with molecular mass of 132 kDa was present only in the serum. It is discussed the possibility of aggregation of 63 kDa protein molecules in the dimers with the formation of a 132 kDa protein in the serum.

[大鼠体组织和血清中第1型透明质酸酶同工型的比较表征]。
经酶谱分析,在肝脏、脾脏、肾乳头、皮肤和血清中鉴定出3种分子量分别为63、73和132 kDa的透明质酸酶蛋白,具有第1型透明质酸酶的性质。在所有研究组织和血清中均检测到分子量为73 kDa的蛋白,而分子量为63 kDa的蛋白仅存在于组织中,分子量为132 kDa的蛋白仅存在于血清中。讨论了63 kDa蛋白分子在二聚体中聚集并在血清中形成132 kDa蛋白的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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