Malignant melanoma of the small bowel presenting with intussusception in a woman: a case report.

IF 0.7 Q4 ONCOLOGY

Melanoma Management Pub Date : 2017-05-01 Epub Date: 2017-05-15 DOI:10.2217/mmt-2016-0028

Abby Vrable, Richard Chang

引用次数: 6

Abstract

Primary malignant melanoma originating in the small bowel is very rare. We report the case of primary malignant melanoma of the small bowel with secondary intussusception in a 51-year-old female with no prior history of cutaneous melanoma. The patient was admitted to the hospital for clinical bowel obstruction after 6 months of varying symptoms of antecedent syncopal events secondary to profound anemia due to iron deficiency followed later by vomiting, abdominal pain and weight loss. A CT scan showed intussusception and she underwent a small bowel resection. Diagnosis of malignant melanoma was confirmed post-operatively following immunohistochemistry. The patient history and postoperative investigation excluded the existence of a primary lesion elsewhere. Our case represents an aggressive primary small bowel melanoma presenting as intussusception.

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女性小肠恶性黑色素瘤伴肠套叠一例报告。

原发性恶性黑色素瘤起源于小肠是非常罕见的。我们报告一例原发性小肠恶性黑色素瘤伴继发性肠套叠的病例，患者为51岁女性，既往无皮肤黑色素瘤病史。患者因临床肠梗阻入院，6个月后出现各种晕厥症状，继发于缺铁引起的深度贫血，随后出现呕吐、腹痛和体重减轻。CT扫描显示肠套叠，她接受了小肠切除术。术后免疫组化诊断为恶性黑色素瘤。患者病史和术后调查排除了其他地方原发病变的存在。本病例为侵袭性原发性小肠黑色素瘤，表现为肠套叠。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Melanoma Management ONCOLOGY-

CiteScore

5.10

自引率

0.00%

发文量

审稿时长

13 weeks

期刊介绍： Skin cancer is on the rise. According to the World Health Organization, 132,000 melanoma skin cancers occur globally each year. While early-stage melanoma is usually relatively easy to treat, once disease spreads prognosis worsens considerably. Therefore, research into combating advanced-stage melanoma is a high priority. New and emerging therapies, such as monoclonal antibodies, B-RAF and KIT inhibitors, antiangiogenic agents and novel chemotherapy approaches hold promise for prolonging survival, but the search for a cure is ongoing. Melanoma Management publishes high-quality peer-reviewed articles on all aspects of melanoma, from prevention to diagnosis and from treatment of early-stage disease to late-stage melanoma and metastasis. The journal presents the latest research findings in melanoma research and treatment, together with authoritative reviews, cutting-edge editorials and perspectives that highlight hot topics and controversy in the field. Independent drug evaluations assess newly approved medications and their role in clinical practice. Key topics covered include: Risk factors, prevention and sun safety education Diagnosis, staging and grading Surgical excision of melanoma lesions Sentinel lymph node biopsy Biological therapies, including immunotherapy and vaccination Novel chemotherapy options Treatment of metastasis Prevention of recurrence Patient care and quality of life.