Epidemiology of cardiovascular risk factors in two population-based studies

4区医学 Q1 Medicine

Atherosclerosis. Supplements Pub Date : 2018-09-01 DOI:10.1016/j.atherosclerosissup.2018.08.003

Elena Olmastroni , Evgeny V. Shlyakhto , Aleksandra O. Konradi , Oxana P. Rotar , Asiiat S. Alieva , Maria A. Boyarinova , Andrea Baragetti , Liliana Grigore , Fabio Pellegatta , Elena Tragni , Alberico L. Catapano , Manuela Casula

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引用次数: 6

Abstract

We aimed to compare cardiovascular risk factors prevalence in Italy and Russia through cross-sectional database analysis.

The study has been based on data from ESSE-RF and from baseline of PLIC study, two population-based epidemiological studies aimed to investigate prevalence of risk factors and evaluating contribution of traditional and new risk factors into morbidity and cardiovascular mortality.

A total of 2203 patients with left and right intima-media thickness (IMT) measurements constituted the source population (1205 from PLIC study and 998 from ESSE-RF study). Sample of ESSE-RF study had slightly more diabetic and hypertensive individuals, while the percentage of subjects with high cholesterol value was lower than in the other sample (67.1% vs 79.9%). The median LDL-C value was higher among individuals not treated with statins in the PLIC sample (p < 0.001), while was comparable among subjects receiving statin therapy. On the other hand, the percentage of individuals with positive cardiovascular history was higher in ESSE-RF sample. This could also explain the higher mean IMT value (0.71 ± 0.17 vs 0.63 ± 0.13) in the whole sample, and among patients without past cardiovascular events (regardless of statin treatment), despite some differences in major risk factors.

Despite Russian and Italian populations are culturally and geographically different, they are not so different based on characteristics analyzed.

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两项基于人群的研究中心血管危险因素的流行病学

我们的目的是通过横断面数据库分析比较意大利和俄罗斯的心血管危险因素患病率。该研究基于ESSE-RF和PLIC研究基线的数据，这两项基于人群的流行病学研究旨在调查危险因素的流行情况，并评估传统和新的危险因素对发病率和心血管死亡率的贡献。共有2203例左右侧内膜-中膜厚度(IMT)测量患者构成源人群(1205例来自PLIC研究，998例来自ESSE-RF研究)。ESSE-RF研究样本中糖尿病和高血压个体略多，而高胆固醇值受试者的百分比低于其他样本(67.1% vs 79.9%)。在PLIC样本中，未接受他汀类药物治疗的患者LDL-C中位数较高(p < 0.001)，而接受他汀类药物治疗的患者LDL-C中位数相当。另一方面，在ESSE-RF样本中，心血管病史阳性的个体百分比更高。这也可以解释尽管主要危险因素存在一些差异，但整个样本和没有心血管事件(无论他汀类药物治疗)的患者的平均IMT值较高(0.71 ± 0.17 vs 0.63 ± 0.13)。尽管俄罗斯人和意大利人在文化和地理上都不同，但从特征分析来看，他们并没有太大的不同。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Atherosclerosis. Supplements 医学-外周血管病

CiteScore

4.80

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Atherosclerosis brings together, from all sources, papers concerned with investigation on atherosclerosis, its risk factors and clinical manifestations.