[Application of Structural Biology in Research on Toxoplasma gondii].

Yan-ping Chen, Dong-dong Wei, Hong-wei Li, Yan-bin Wei, Kun Yin
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Abstract

Structural biology is a rapidly-developing comprehensive discipline that interprets the atom-level assembling, interaction and movement between molecules. This paper summarizes basic methods in structural biology, with a focus on structure research progress of Toxoplasma gondii rhoptry and calmodulin-like domain protein kinase, to illustrate the application of structural biology in research on important virulence factors and drug targets of T. gondii.

结构生物学在刚地弓形虫研究中的应用
结构生物学是一门快速发展的综合性学科,主要研究分子之间的原子水平组装、相互作用和运动。本文综述了结构生物学的基本方法,重点介绍了刚地弓形虫体和钙调蛋白样结构域蛋白激酶的结构研究进展,说明结构生物学在刚地弓形虫重要毒力因子和药物靶点研究中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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