[A new triterpenic acid from the roots of Rosa laevigata].

药学学报 Pub Date : 2017-03-01
Yu-lu Li, Hua-nian Dai, Guo-xu Ma, Wen Zhang, Tong-yu Wu, Yun-qing Wang, Jie-ming Zou, Xiao-qing Zhong, Yan-lin Zhou, Jing-quan Yuan, Xu-dong Xu, Wei Yi
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引用次数: 0

Abstract

This study was designed to investigate triterpenoids from the roots of Rosa laevigata Michx. The silica gel column chromatography was used to separate the chemical constituents from the roots of Rosa laevigata Michx. HPLC was used to analyze its purity and chemical constitution. Spectroscopy methods were used to determine their structures. Five constituents were isolated and identified as19α-OH-3β-E-feruloyl corosolic acid (1), 23-hydroxy-tormentic acid (2), 2α, 3β, 19α, 23- tetrahydroxy-12-en-28-oleanolic acid (3), 2α, 3α, 20β- trihydroxyurs-13 (18)-en-28-oic-acid (4), 2α, 3β, 20β-trihydroxyurs-13 (18)-en-28-oic-acid (5). Compound 1 was assigned as a new compound, compounds 4, 5 were obtained from the genus Rosa for the first time.

[从玫瑰根部提取的一种新的三萜酸]。
本研究旨在研究月季(Rosa laevigata micx)根中的三萜。采用硅胶柱层析法分离了蔷薇根的化学成分。采用高效液相色谱法分析其纯度和化学成分。用光谱学方法测定了它们的结构。分离得到5个化合物,鉴定为19α- oh -3β- e -阿魏酰corosolicacid(1), 23-羟基拷问酸(2),2α, 3β, 19α, 23-四羟基-12-en-28齐墩果酸(3),2α, 3α, 20β-三羟基-13 (18)-en-28-oic-acid (4), 2α, 3β, 20β-三羟基-13 (18)-en-28-oic-acid(5)。化合物1为新化合物,化合物4,5为首次从Rosa属植物中分离得到。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
药学学报
药学学报 Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
1.20
自引率
0.00%
发文量
0
期刊介绍: Acta Pharmaceutica Sinica B (APSB) is a bimonthly English peer-reviewed online journal in ScienceDirect, which publishes significant original research articles, communications and high quality reviews of recent advances. APSB encourages submissions from all areas of pharmaceutical sciences, including pharmacology, pharmaceutics, medicinal chemistry, natural products, pharmacognosy, pharmaceutical analysis and pharmacokinetics. APSB is a part of the series Acta Pharmaceutica Sinica, which was founded in 1953. The journal is co-published by Elsevier B.V., in association with the Institute of MateriaMedica, Chinese Academy of Medical Sciences and Chinese Pharmaceutical Association.
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