Sinonasal epithelial-myoepithelial carcinoma: Report of a novel subsite and review of the literature.

IF 2.3 Q1 OTORHINOLARYNGOLOGY

Allergy & Rhinology Pub Date : 2018-04-09 eCollection Date: 2018-01-01 DOI:10.1177/2152656718764229

Theodore A Schuman, Adam J Kimple, Claire H Edgerly, Charles S Ebert, Adam M Zanation, Brian D Thorp

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Abstract

Background: Epithelial-myoepithelial carcinoma (EMC) is a rare tumor of the major and minor salivary glands. Sinonasal EMC is extremely uncommon and hitherto not described within the frontal or ethmoid sinuses.

Objective: To present a novel sinonasal subsite and review the literature regarding sinonasal EMC.

Methods: A case of frontoethmoidal EMC was presented. A medical literature data base was queried from January 1, 1950, to August 8, 2017, for all reports of sinonasal EMC.

Results: A 69-year-old man underwent combined open and endoscopic craniofacial resection of a right frontoethmoidal EMC, a previously undescribed primary location for this tumor. A comprehensive review of the literature revealed 13 additional cases of sinonasal EMC.

Conclusion: EMC is an uncommon neoplasm typically found in the major salivary glands; occurrence in the nose or paranasal sinuses is extremely rare. EMC often follows an indolent clinical course, although, in a minority of cases, particularly in large tumors with nuclear atypia, more aggressive behavior may be observed.

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鼻窦上皮-肌上皮癌：一个新亚站的报告和文献综述。

背景：上皮-肌上皮癌（EMC）是一种罕见的大、小唾液腺肿瘤。鼻窦 EMC 极其罕见，迄今为止尚未在额窦或筛窦中发现：介绍一种新的鼻窦亚部位并回顾有关鼻窦 EMC 的文献：方法：介绍一例额窦EMC病例。方法：介绍一例前牙状EMC病例，并查询从1950年1月1日至2017年8月8日的医学文献数据库，以了解所有关于鼻窦EMC的报道：一名69岁的男性接受了开颅和内窥镜颅面联合切除术，切除了右侧前牙乳突EMC，该肿瘤的原发部位此前未被描述过。通过全面查阅文献，我们又发现了13例鼻窦EMC病例：结论：EMC 是一种不常见的肿瘤，通常发生在主要唾液腺；发生在鼻腔或副鼻窦的情况极为罕见。尽管在少数病例中，特别是在核不典型的大肿瘤中，可能会观察到更具侵袭性的行为，但 EMC 的临床病程通常较为平缓。

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