Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults: A pilot study.

Q3 Medicine

Nutrition and Healthy Aging Pub Date : 2018-06-15 DOI:10.3233/NHA-170036

Kelsey Gabel, Kristin K Hoddy, Nicole Haggerty, Jeehee Song, Cynthia M Kroeger, John F Trepanowski, Satchidananda Panda, Krista A Varady

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引用次数: 340

Abstract

Background: Time restricted feeding decreases energy intake without calorie counting and may be a viable option for weight loss. However, the effect of this diet on body weight in obese subjects has never been examined.

Objective: This study investigated the effects of 8-h time restricted feeding on body weight and metabolic disease risk factors in obese adults.

Design: Obese subjects (n = 23) participated in an 8-h time restricted feeding intervention (ad libitum feeding between 10:00 to 18:00 h, water fasting between 18:00 to 10:00 h) for 12 weeks. Weight loss and other outcomes were compared to a matched historical control group (n = 23).

Results: Body weight and energy intake decreased in the time restricted group (-2.6% ± 0.5; -341 ± 53 kcal/d) relative to controls over 12 weeks (P < 0.05). Systolic blood pressure decreased in the time restricted feeding group (-7 ± 2 mm Hg) versus controls (P < 0.05). Fat mass, lean mass, visceral fat mass, diastolic blood pressure, LDL cholesterol, HDL cholesterol, triglycerides, fasting glucose, fasting insulin, HOMA-IR, and homocysteine were not significantly different from controls after 12 weeks (no group×time interaction).

Conclusion: These findings suggest that 8-h time restricted feeding produces mild caloric restriction and weight loss, without calorie counting. It may also offer clinical benefits by reducing blood pressure.

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8小时限食对肥胖成人体重和代谢性疾病危险因素的影响:一项初步研究

背景:时间限制喂养减少能量摄入而不计算卡路里，可能是减肥的可行选择。然而，这种饮食对肥胖受试者体重的影响从未被研究过。目的:探讨8小时限饲对肥胖成人体重及代谢性疾病危险因素的影响。设计:肥胖受试者(n = 23)参加8小时限制性喂养干预(10:00 - 18:00随意喂养，18:00 - 10:00禁食)，为期12周。体重减轻和其他结果与匹配的历史对照组(n = 23)进行比较。结果:时间限制组体重和能量摄入下降(-2.6%±0.5;-341±53 kcal/d)，在12周内相对于对照组(P P)。结论:这些研究结果表明，8 h限制喂养产生轻度热量限制和体重减轻，不计算卡路里。它还可以通过降低血压提供临床益处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nutrition and Healthy Aging Agricultural and Biological Sciences-Food Science

CiteScore

1.70

自引率

0.00%

发文量

期刊介绍： Nutrition and Healthy Aging is an international forum for research on nutrition as a means of promoting healthy aging. It is particularly concerned with the impact of nutritional interventions on the metabolic and molecular mechanisms which modulate aging and age-associated diseases, including both biological responses on the part of the organism itself and its micro biome. Results emanating from both model organisms and clinical trials will be considered. With regards to the latter, the journal will be rigorous in only accepting for publication well controlled, randomized human intervention trials that conform broadly with the current EFSA and US FDA guidelines for nutritional clinical studies. The journal will publish research articles, short communications, critical reviews and conference summaries, whilst open peer commentaries will be welcomed.