Paraneoplastic Erythema Nodosum as a Prelude to Hodgkin Lymphoma.

Q4 Medicine

Connecticut Medicine Pub Date : 2017-03-01

Yazeed Samara, Justin Thomas, Constantin A Dasanu

引用次数: 0

Abstract

Erythema nodosum is currently thought to represent a delayed hypersensitivity reac- tion to deposition of circulating immune complexes, followed by neutrophilic infiltration of the septa in the subcutaneous tissue. We describe a patient with advanced Hodgkin lymphoma with B symptoms, preceded by erythema nodosum of the left shin by 12 weeks. This dermatologic entity cleared after the treatment for Hodgkin lymphoma, suggesting a true paraneoplastic reaction. Given its known temporal association with Hodgkin lymphoma, we believe that this link deserves more exploration in both re- search laboratories and clinical practice.

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副肿瘤结节性红斑是霍奇金淋巴瘤的前奏。

结节性红斑目前被认为是对循环免疫复合物沉积的迟发性超敏反应，随后是皮下组织中隔的中性粒细胞浸润。我们描述了一位晚期霍奇金淋巴瘤患者，伴有B型症状，前12周出现左胫骨结节性红斑。该皮肤实体在霍奇金淋巴瘤治疗后清除，提示真正的副肿瘤反应。鉴于其已知的与霍奇金淋巴瘤的时间关联，我们认为这种联系值得在研究实验室和临床实践中进行更多的探索。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Connecticut Medicine Medicine-Medicine (all)

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期刊介绍： The Connecticut State Medical Society (CSMS) is a federation of eight component county medical associations, with a total membership exceeding 7,000 physicians. CSMS itself is a constituent state entity of the American Medical Association. Founded by the physician-patriots of the American Revolution, the Society operates from a heritage of democratic principles embodied in its Charter and Bylaws. The base of all authority in CSMS is, of course, the individual physician member. It is the decisions of members in their own county associations that ultimately determine the nature of the Society"s policies and activities.