Mechanism of Repetitive Transcranial Magnetic Stimulation for Depression.

Zhengwu Peng, Cuihong Zhou, Shanshan Xue, Jie Bai, Shoufen Yu, Xiaosa Li, Huaning Wang, Qingrong Tan
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引用次数: 52

Abstract

Depressive disorder is one of the most common mental health problems currently. However, the mechanism-based treatments for this disorder remain elusive. Repetitive transcranial magnetic stimulation (rTMS), a non-invasive procedure that could stimulate electrical activity by a pulsed magnetic field in the brain, is considered to be an effective treatment for depression. Here, we review the main findings from both clinical and basic research on rTMS for depression, including its antidepressant efficacy, basic principles, as well as its ability to regulate neural circuits, neurotransmitters and brain networks, neurogenesis in hippocampus, and synaptic, and molecular pathways.

重复经颅磁刺激治疗抑郁症的机制。
抑郁症是目前最常见的心理健康问题之一。然而,基于机制的治疗这种疾病仍然难以捉摸。重复经颅磁刺激(rTMS)是一种非侵入性的方法,可以通过脉冲磁场刺激大脑中的电活动,被认为是治疗抑郁症的有效方法。本文综述了rTMS治疗抑郁症的临床和基础研究的主要成果,包括rTMS的抗抑郁疗效、基本原理、调节神经回路、神经递质和脑网络、海马神经发生、突触和分子通路的能力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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