Status Investigation of Outpatients Receiving Methadone Maintenance Treatment (MMT) in Shanghai from 2005 to 2016.

Jiayi Bao, Lei Zhang, Zhen Ning, Jie Fu, Min Zhao, Jiang DU
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引用次数: 2

Abstract

Background: Methadone maintenance treatment (MMT) is an effective measure to control drug abuse, prevent AIDS, and improve family and social functions among those with heroin addiction. Relevant surveys in recent years show that the number of outpatients receiving MMT has a downward trend.

Aims: To understand variation in maintenance treatment rates and causes of withdrawal for outpatients receiving MMT in Shanghai since initiation of this program.

Method: This study was a retrospective investigation, with data from the AIDS Comprehensive Prevention and Control Data Information Management System of the China AIDS Prevention and Control Center. Descriptive statistics were used to describe demographic data, treatment maintenance rate, and number of new outpatients receiving MMT in Shanghai From May 2005 to June 2016. The causes of withdrawal were summarized and analyzed.

Results: From May 2005 to June 2016, there were a total of 7181 outpatients receiving MMT in Shanghai. These patients were primarily male (male to female ratio around 3:1), young adults (more than 90% of these patients were 25 to 54 years old), with junior high school education level and below (65.4%), single (total of unmarried, divorced and widowed: 63.1%), and unemployed or underemployed (81.5%). The daily dose of methadone in MMT patients showed an upward trend since 2008, and gradually declined after reaching its peak in 2013. The mean (sd) dose of methadone taken in the years studied was 56 (2.75) ml/d. The number of new outpatients increased sharply in 2007 and 2008 (more than 1500), and then decreased year by year. The number of outpatients had increased continuously from 2005 to 2011, with the peak in 2011 (3840 patients), and then decreased gradually. The maintenance rate was stable at over 80% since 2010. The main causes of withdrawal: 1) arrested due to unrelated criminal causes (19.89%), 2) sent to compulsory isolated rehabilitation center due to occasional drug use, and 3) physical reasons (disease/pregnancy/death, 11.80%).

Conclusion: The maintenance rate has been kept at a relatively good level since the initiation of the MMT outpatient clinic service in Shanghai. The number of patients receiving treatment showed an increase-then-decrease trend. The main causes of patients' withdrawal were mainly related to "crime" and "relapse". In order to make MMT outpatient service better, subsequent studies need to carry out related investigations to understand the causes of these changes and patients reasons for withdrawal.

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2005 - 2016年上海市门诊美沙酮维持治疗(MMT)患者现状调查
背景:美沙酮维持治疗(MMT)是控制海洛因依赖者药物滥用、预防艾滋病、改善家庭和社会功能的有效措施。近年来的相关调查显示,接受MMT的门诊人数呈下降趋势。目的:了解自MMT项目启动以来,上海市门诊接受MMT的患者维持治疗率的变化和退出原因。方法:采用回顾性调查方法,数据来源于中国艾滋病预防控制中心艾滋病综合防治数据信息管理系统。采用描述性统计方法对上海市2005年5月至2016年6月接受MMT的人口统计数据、治疗维持率和新增门诊人数进行描述。总结并分析了停药的原因。结果:2005年5月至2016年6月,上海市共有7181例门诊患者接受MMT治疗。这些患者主要为男性(男女比例约为3:1)、青壮年(25 ~ 54岁占90%以上)、初中及以下文化程度(65.4%)、单身(未婚、离婚、丧偶占63.1%)、失业或半就业占81.5%。MMT患者的日美沙酮剂量自2008年以来呈上升趋势,2013年达到峰值后逐渐下降。在研究年份中,美沙酮的平均(sd)剂量为56 (2.75)ml/d。2007年和2008年新增门诊人数急剧增加(超过1500人),之后逐年下降。门诊人数从2005年到2011年持续增加,2011年达到高峰(3840人),之后逐渐下降。自2010年以来,维护率稳定在80%以上。戒毒的主要原因为:1)无关联犯罪被捕(19.89%),2)偶尔吸毒送入强制隔离康复中心,3)身体原因(疾病/怀孕/死亡,11.80%)。结论:上海市MMT门诊服务开展以来,维持率一直保持在较好的水平。治疗人数呈先增加后减少的趋势。患者戒断的主要原因主要与“犯罪”和“复发”有关。为了更好地开展MMT门诊服务,后续研究需要开展相关调查,了解这些变化的原因以及患者退出的原因。
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来源期刊
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期刊介绍: Shanghai archives of psychiatry (bimonthly) was founded in 1959 and is sponsored by Shanghai Mental Health Center. The journal is aimed at mental health workers across the country, including psychiatrists and nurses, clinical psychologists, social workers, and people who are committed to the cause of mental health. It focuses on reporting clinical research results and practical experience in the field of psychiatry, and introduces the latest knowledge in psychiatry and related fields. The columns include monographs, case reports, clinical case discussions, reviews, mental health and law, and debates and discussions.
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