Seroprevalences and Correlates of Hepatitis B and C Among Cameroonian Pregnant Women.

Clinical Medicine Insights-Reproductive Health Pub Date : 2018-04-16 eCollection Date: 2018-01-01 DOI:10.1177/1179558118770671

Florent Ymele Fouelifack, Jeanne Hortence Fouedjio, Jovanny Tsuala Fouogue, Loic Dongmo Fouelifa

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引用次数: 13

Abstract

Background and rationale: Viral hepatitis B (VHB) and viral hepatitis C (VHC) are major public health issues in resource-poor countries where vertical transmission remains high.

Aim: To assess prevalences and correlates of VHB and VHC among women attending antenatal clinic.

Methods: A cross-sectional study at the Yaounde Central Hospital from January 1 to June 30, 2016. We included 360 pregnant women who were screened for hepatitis B virus surface antigen (HbsAg) and VHCAb by rapid diagnostic test (DiaSpot Diagnostics, USA) followed by confirmation of positive results by a reference laboratory. Odds ratios (95% confidence interval [CI]) were used to measure associations between variables. Statistical significance was set for P-value <.05.

Results: Mean age was 27.9 ± 5.6 years. The prevalences of HbsAg and VHCAb were 9.4% (n = 34) and 1.7% (n = 6), respectively. Multiplicity of sex partners was significantly associated with HbsAg positivity (adjusted odds ratio [aOR]: 11.6; 95% CI: 5.1-26.7; P < .001) while none of the studied factors was associated with VHCAb.

Conclusion: The high prevalence of hepatitis B among pregnant women supports systematic screening and free vaccination of pregnant women and women of childbearing age.

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喀麦隆孕妇乙型和丙型肝炎血清患病率及其相关因素

背景和理由:病毒性乙型肝炎(VHB)和病毒性丙型肝炎(VHC)是资源贫乏国家的主要公共卫生问题，这些国家的垂直传播仍然很高。目的:了解产前门诊妇女VHB和VHC的患病率及其相关因素。方法:2016年1月1日至6月30日在雅温得中心医院进行横断面研究。我们纳入了360名孕妇，她们通过快速诊断试验(美国DiaSpot诊断公司)筛查乙型肝炎病毒表面抗原(HbsAg)和VHCAb，然后由参比实验室确认阳性结果。比值比(95%置信区间[CI])用于测量变量之间的相关性。p值结果:平均年龄27.9±5.6岁。HbsAg和VHCAb的患病率分别为9.4% (n = 34)和1.7% (n = 6)。性伴侣数量与HbsAg阳性显著相关(调整优势比[aOR]: 11.6;95% ci: 5.1-26.7;结论:乙型肝炎在孕妇中的高患病率支持对孕妇和育龄妇女进行系统筛查和免费接种。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Medicine Insights-Reproductive Health OBSTETRICS & GYNECOLOGY-

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： Clinical Medicine Insights: Reproductive Health is a peer reviewed; open access journal, which covers all aspects of Reproduction: Gynecology, Obstetrics, and Infertility, spanning both male and female issues, from the physical to the psychological and the social, including: sex, contraception, pregnancy, childbirth, and related topics such as social and emotional impacts. It welcomes original research and review articles from across the health sciences. Clinical subjects include fertility and sterility, infertility and assisted reproduction, IVF, fertility preservation despite gonadotoxic chemo- and/or radiotherapy, pregnancy problems, PPD, infections and disease, surgery, diagnosis, menopause, HRT, pelvic floor problems, reproductive cancers and environmental impacts on reproduction, although this list is by no means exhaustive Subjects covered include, but are not limited to: • fertility and sterility, • infertility and ART, • ART/IVF, • fertility preservation despite gonadotoxic chemo- and/or radiotherapy, • pregnancy problems, • Postpartum depression • Infections and disease, • Gyn/Ob surgery, • diagnosis, • Contraception • Premenstrual tension • Gynecologic Oncology • reproductive cancers • environmental impacts on reproduction, • Obstetrics/Gynaecology • Women''s Health • menopause, • HRT, • pelvic floor problems, • Paediatric and adolescent gynaecology • PID