Simple retrograde cerebral perfusion is as good as complex antegrade cerebral perfusion for hemiarch replacement.

Journal of visualized surgery Pub Date : 2018-03-13 eCollection Date: 2018-01-01 DOI:10.21037/jovs.2018.02.10
Akiko Tanaka, Anthony L Estrera
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引用次数: 9

Abstract

Cerebral complication is a major concern after aortic arch surgery, which may lead to death. Thus, cerebral protection strategy plays the key role to obtain respectable results in aortic arch repair. Deep hypothermic circulatory arrest was introduced in 1970s to decrease the ischemic insults to the brain. However, safe duration of circulatory arrest time was limited to 30 minutes. The 1990s was the decade of evolution for cerebral protection, in which two adjuncts for deep hypothermic circulatory arrest were introduced: retrograde and antegrade cerebral perfusion (ACP) techniques. These two cerebral perfusion techniques significantly decreased incidence of postoperative neurological dysfunction and mortality after aortic arch surgery. Although there are no large prospective studies that demonstrate which perfusion technique provide better outcomes, multiple retrospective studies implicate that ACP may decrease cerebral complications compared to retrograde cerebral perfusion (RCP) when a long circulatory arrest time is required during aortic arch reconstructions. To date, many surgeons favor ACP over RCP during a complex aortic arch repair, such as total arch replacement and hybrid arch replacement. However, the question is whether the use of ACP is necessary during a short, limited circulatory arrest time, such as hemiarch replacement? There is a paucity of data that proves the advantages of a complex ACP over a simple RCP for a short circulatory arrest time. RCP with deep hypothermic circulatory arrest is the simple, efficient cerebral protection technique with minimal interference to the surgical field-and it potentially allows to flush atheromatous debris out from the arch vessels. Thus, it is the preferred adjunct to deep hypothermic circulatory arrest during hemiarch replacement in our institution.

单纯的逆行脑灌注与复杂的顺行脑灌注在充血置换中的效果一样好。
脑并发症是主动脉弓手术后的主要问题,可能导致死亡。因此,脑保护策略在主动脉弓修复中起着重要的作用。深度低温循环停搏是在20世纪70年代提出的,目的是减少缺血性脑损伤。然而,循环停止的安全时间限制为30分钟。20世纪90年代是脑保护发展的十年,深度低温循环停止的两种辅助技术被引入:逆行和顺行脑灌注(ACP)技术。这两种脑灌注技术显著降低了主动脉弓术后神经功能障碍的发生率和死亡率。虽然没有大型前瞻性研究证明哪种灌注技术能提供更好的结果,但多项回顾性研究表明,当主动脉弓重建需要较长的循环停搏时间时,ACP比逆行脑灌注(RCP)可减少脑并发症。迄今为止,在复杂的主动脉弓修复中,如全弓置换术和混合弓置换术,许多外科医生更倾向于ACP而不是RCP。然而,问题是在短暂的有限循环停搏时间内是否有必要使用ACP,例如充血置换?在短的循环停搏时间内,证明复杂ACP优于简单RCP的数据很少。深度低温循环停止的RCP是一种简单、有效的脑保护技术,对手术视野的干扰最小,并且有可能将动脉粥样硬化碎片从弓血管中冲洗出来。因此,在我们的机构中,它是在充血置换期间深度低温循环停止的首选辅助手段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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