Acute Hepatic Allograft Rejection in Pediatric Recipients: Effective Factors.

IF 0.3 Q4 TRANSPLANTATION
International Journal of Organ Transplantation Medicine Pub Date : 2018-01-01 Epub Date: 2018-02-01
S M Dehghani, I Shahramian, M Afshari, M Bahmanyar, M Ataollahi, A Sargazi
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引用次数: 0

Abstract

Background: Acute cellular rejection (ACR), a reversible process, can affect the graft survival.

Objective: To evaluate the relation between ACR and clinical factors in recipients of allograft liver transplantation.

Methods: 47 recipients of liver were consecutively enrolled in a retrospective study. Their information were retrieved from their medical records and analyzed.

Results: Of the 47 recipients, 38 (81%) experienced acute rejection during 24 months of the transplantation. None of the studied factors for occurring transplant rejection, i.e., blood groups, sex, age, familial history of disease, receiving drugs and blood products, type of donor, Child score, and Child class, was not found to be significant.

Conclusion: During a limited follow-up period, we did not find any association between ACR and suspected risk factors.

儿童肝移植急性排斥反应:影响因素。
背景:急性细胞排斥反应(ACR)是一个可逆的过程,可影响移植物的存活。目的:探讨同种异体肝移植受者ACR与临床因素的关系。方法:对47例肝移植受者进行回顾性研究。研究人员从他们的医疗记录中检索并分析了他们的信息。结果:47例受者中,38例(81%)在移植24个月内出现急性排斥反应。所研究的发生移植排斥反应的因素,即血型、性别、年龄、疾病家族史、接受药物和血液制品、供体类型、儿童评分和儿童类别,均未发现有显著性。结论:在有限的随访期间,我们未发现ACR与可疑危险因素之间存在任何关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
0
审稿时长
12 weeks
期刊介绍: The International Journal of Organ Transplantation Medicine (IJOTM) is a quarterly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research on transplantation. The scope of the journal includes organ and tissue donation, procurement and preservation; surgical techniques, innovations, and novelties in all aspects of transplantation; genomics and immunobiology; immunosuppressive drugs and pharmacology relevant to transplantation; graft survival and prevention of graft dysfunction and failure; clinical trials and population analyses in the field of transplantation; transplant complications; cell and tissue transplantation; infection; post-transplant malignancies; sociological and ethical issues and xenotransplantation.
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